Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 7/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 2/20 | 0.36 |
| ▸ | FNTB | P49356 | 2/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.34 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25937750 | 0.85 | SIGMAR1 (0.41) | EGFRSIGMAR1MEN1ALDH1A1TSHR | |
| SCHEMBL25937866 | 0.80 | TP53 (0.40) | EGFRSIGMAR1AURKB | |
| SCHEMBL25937580 | 0.80 | SIGMAR1 (0.40) | SIGMAR1MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL25937403 | 0.79 | KCNQ2 (0.41) | SIGMAR1MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL25937888 | 0.77 | EGFR (0.43) | EGFRDRD2NOTUM | |
| SCHEMBL25937424 | 0.76 | NOTUM (0.53) | SIGMAR1ALDH1A1DRD2NOTUM | |
| SCHEMBL25937779 | 0.74 | KDR (0.43) | SIGMAR1MEN1KMT2A | |
| SCHEMBL25937688 | 0.74 | SIGMAR1 (0.38) | EGFRSIGMAR1MEN1ALDH1A1TSHR | |
| SCHEMBL30557580 | 0.73 | KCNQ2 (0.46) | SIGMAR1MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL25937545 | 0.73 | KCNQ2 (0.46) | SIGMAR1MEN1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |