SCHEMBL2594052

SCHEMBL2594052

CCOc1cc2ccccc2[nH]1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 2/20 0.50
PDGFRA P16234 2/20 0.50
LOXL2 Q9Y4K0 1/20 0.48
AOC3 Q16853 2/20 0.48
KDM4E B2RXH2 6/20 0.47
ALDH1A1 P00352 4/20 0.47
MAPT P10636 3/20 0.47
BRD4 O60885 1/20 0.43
GAA P10253 1/20 0.42
MAPK1 P28482 1/20 0.42
LMNA P02545 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CA2 P00918 1/20 0.42
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB1 P18505 1/20 0.41
GABRG2 P18507 1/20 0.41
GABRB3 P28472 1/20 0.41
GABRA5 P31644 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4273420 0.85 MAPT (0.45) PDGFRBPDGFRALOXL2AOC3KDM4E
SCHEMBL4265909 0.84 DRD2 (0.46) PDGFRBPDGFRALOXL2AOC3KDM4E
SCHEMBL7084107 0.82 GPR84 (0.45) PDGFRBPDGFRAKDM4EALDH1A1MAPT
SCHEMBL7207164 0.81 LOXL2 (0.50) LOXL2AOC3KDM4EALDH1A1MAPT
SCHEMBL5557187 0.80 LOXL2 (0.49) PDGFRBPDGFRALOXL2AOC3KDM4E
SCHEMBL31370881 0.80 KDM4E (0.41) PDGFRBPDGFRALOXL2AOC3KDM4E
SCHEMBL7987458 0.78 AR (0.42) LOXL2AOC3KDM4EALDH1A1MAPT
SCHEMBL3182479 0.78 PDGFRB (0.52) PDGFRBPDGFRALOXL2AOC3KDM4E
SCHEMBL30066143 0.78 PDGFRB (0.52) PDGFRBPDGFRALOXL2AOC3KDM4E
SCHEMBL7775103 0.78 AR (0.42) PDGFRBPDGFRALOXL2AOC3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103966585-B The method of silicate passivating solution and passivation zinc-coated wire overlay coating SHANGHAI UNIVERSITY (CN) 2016-05-25 CN claimed
EP-4707264-A2 COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS Verbio SE (DE) 2026-03-11 EP disclosed
EP-4122924-B1 COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS VERBIO SE (DE) 2025-11-19 EP disclosed
US-20250108081-A1 Improved Probiotic Potency of the Yeast Saccharomyces Boulardii VIB VZW (BE) 2025-04-03 US disclosed
US-12215310-B2 Means and methods to modulate probiotic potency of the yeast Saccharomyces boulardii VIB VZW (BE) 2025-02-04 US disclosed
WO-2024260476-A1 METHOD FOR PREPARING INTRACELLULAR-DERIVED NANOVESICLES AND USE OF NANOVESICLES 天津医科大学眼科医院 2024-12-26 WO disclosed
US-12065450-B2 Compounds and the use thereof in metathesis reactions VERBIO SE (DE) 2024-08-20 US disclosed
WO-2023144274-A1 IMPROVED PROBIOTIC POTENCY OF THE YEAST SACCHAROMYCES BOULARDII VIB VZW (BE) 2023-08-03 WO disclosed
EP-4122924-A2 COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS Verbio Vereinigte BioEnergie AG (DE) 2023-01-25 EP disclosed
US-20230013959-A1 COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS VERBIO SE (DE) 2023-01-19 US disclosed
CN-103966585-B The method of silicate passivating solution and passivation zinc-coated wire overlay coating SHANGHAI UNIVERSITY (CN) 2016-05-25 CN disclosed
WO-2015155593-A1 COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS XIMO AG (CH) 2015-10-15 WO disclosed
WO-2011139242-A2 PROCESS FOR THE PREPARATION OF 2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE DERIVATIVES USTAV EXPIREMENTÁLNEJ FARMAKOLÓGIE A TOXIKOLÓGIE SAV (SK) 2011-11-10 WO disclosed
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20090253713-A1 Small Molecule Compositions for Sexual Dysfunction PALATIN TECHNOLOGIES, INC. (US) 2009-10-08 US disclosed
US-7550602-B1 Small molecule compositions for sexual dysfunction PALATIN TECHNOLOGIES, INC. (US) 2009-06-23 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed
US-7396814-B2 Metallopeptide compositions for treatment of sexual dysfunction PALATIN TECHNOLOGIES, INC. (US) 2008-07-08 US disclosed
US-6238439-B1 DYEING HAIR WITH IODIDE-FREE, TWO-COMPONENT DYE COMPRISING INDOLE COMPOUND AND AN AQUEOUS ALKALINE OXIDIZER SOLUTION OF HYDROGEN PEROXIDE, UREA PEROXIDE, A PERCARBONATE OR A PERBORATE L'OREAL (FR) 2001-05-29 US disclosed
US-4138396-A Pyridyl-azo-indolyl cationic dyes CIBA-GEIGY CORPORATION (US) 1979-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12065450-B2 Compounds and the use thereof in metathesis reactions PRMT6, CYP2D6, POR PDGFRB 2356/4885PDGFRA 2090/4885LOXL2 2212/4885
US-20090253713-A1 Small Molecule Compositions for Sexual Dysfunction PDE3B, PDE3A, PDE5A PDGFRB 1634/4885PDGFRA 2068/4885LOXL2 3675/4885
US-20230013959-A1 COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS PRMT6, CYP2D6, POR PDGFRB 2356/4885PDGFRA 2090/4885LOXL2 2212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.