Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22479880 | 0.87 | ADRA1A (0.41) | RXRAADRA1AADRA1BMEN1MAPT | |
| SCHEMBL23902029 | 0.83 | RXRA (0.45) | RXRAADRA1AADRA1BMEN1MAPT | |
| SCHEMBL9908241 | 0.82 | HRH4 (0.45) | RXRAMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL18929928 | 0.81 | ALDH1A1 (0.36) | ADRA1AADRA1BMEN1MAPTKMT2A | |
| SCHEMBL9607585 | 0.81 | KMT2A (0.45) | RXRAMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL9945958 | 0.78 | ALDH1A1 (0.44) | RXRAMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL12598685 | 0.77 | FFAR1 (0.46) | ADRA1AADRA1BMEN1MAPTKMT2A | |
| SCHEMBL12868968 | 0.77 | KCNK3 (0.43) | PDE2AARHRH4SLC6A4 | |
| SCHEMBL28935348 | 0.77 | MAPT (0.47) | ADRA1AADRA1BMEN1MAPTKMT2A | |
| SCHEMBL24869064 | 0.77 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242504-A1 | DEUTERIUM-ENRICHED PIPERIDINONYL-OXOISOINDOLINYL ACETAMIDES AND METHODS OF TREATING MEDICAL DISORDERS USING SAME | DEUTERX LLC (US) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242504-A1 | DEUTERIUM-ENRICHED PIPERIDINONYL-OXOISOINDOLINYL ACETAMIDES AND METHODS OF TREATING MEDICAL DISORDERS USING SAME | EGLN3, HPGDS, EGLN2 | RXRA 2236/4885ADRA1A 2965/4885ADRA1B 3727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.