SCHEMBL25944862

SCHEMBL25944862

CC(C)NC(CCCCNC(=O)CCOCCN=[N+]=[N-])C(N)=O

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ ALB P02768 9/20 0.36
▸ GLP1R P43220 8/20 0.32
▸ SIRT5 Q9NXA8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26225750 0.89 ALB (0.37) ALBGLP1RSIRT5
SCHEMBL26759938 0.84 GLP1R (0.38) ALBGLP1R
SCHEMBL26225768 0.82 ALB (0.33) ALB
SCHEMBL25944453 0.80 ALB (0.33) ALB
SCHEMBL25944773 0.79 GLP1R (0.37) ALBGLP1RSIRT5
SCHEMBL23544192 0.78 GLP1R (0.53) GLP1R
SCHEMBL20980230 0.77 ALB (0.38) ALB
SCHEMBL29328700 0.77 TSHR (0.35) —
SCHEMBL29072106 0.77 GLP1R (0.49) ALBGLP1R
SCHEMBL24630340 0.77 GLP1R (0.49) ALBGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331801-A1 IL-2R-BETA-GAMMA BINDING COMPOUNDS MEDIKINE, INC. (US) 2023-10-19 — — US disclosed
US-11718654-B2 IL-2R-βγ binding compounds MEDIKINE, INC. (US) 2023-08-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331801-A1 IL-2R-BETA-GAMMA BINDING COMPOUNDS IL2RA, IL2, IL15RA ALB 1363/4885GLP1R 317/4885SIRT5 3158/4885
US-11718654-B2 IL-2R-βγ binding compounds IL2RA, IL2, IL1RN ALB 2282/4885GLP1R 306/4885SIRT5 3233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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