SCHEMBL26225768

SCHEMBL26225768

CC(=O)C(CCCCNC(=O)CCOCCN=[N+]=[N-])C(N)=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ALB P02768 4/20 0.33
▸ TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26225750 0.84 ALB (0.37) ALB
SCHEMBL25944862 0.82 ALB (0.36) ALB
SCHEMBL25944453 0.80 ALB (0.33) ALBTSHR
SCHEMBL29328700 0.79 TSHR (0.35) TSHR
SCHEMBL24629997 0.78 CASP2 (0.49) —
SCHEMBL26346638 0.78 GLP1R (0.40) ALBTSHR
SCHEMBL15076070 0.77 SLC6A5 (0.40) TSHR
SCHEMBL24920307 0.76 TSHR (0.35) TSHR
SCHEMBL24332556 0.75 CASP2 (0.54) ALB
SCHEMBL24630340 0.74 GLP1R (0.49) ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357358-A1 IL-7R-ALPHA-GAMMA BINDING COMPOUNDS BLUEBIRD VENTURES I, L.P. 2023-11-09 — — US disclosed
US-11746139-B2 IL-7Rαγc binding compounds MEDIKINE, INC. (US) 2023-09-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11746139-B2 IL-7Rαγc binding compounds IL2RA, IL23R, IL6ST ALB 2633/4885TSHR 267/4885
US-20230357358-A1 IL-7R-ALPHA-GAMMA BINDING COMPOUNDS IL2RA, IL2, IL6ST ALB 1918/4885TSHR 326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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