SCHEMBL25947685

SCHEMBL25947685

CC1(C)OB(c2cccn2F)OC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LPL P06858 13/20 0.40
LIPG Q9Y5X9 13/20 0.40
JAK2 O60674 2/20 0.33
BTK Q06187 2/20 0.33
P2RX7 Q99572 1/20 0.32
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA9 Q16790 2/20 0.31
CA12 O43570 1/20 0.31
CA3 P07451 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA7 P43166 1/20 0.31
CA14 Q9ULX7 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
MAPK1 P28482 1/20 0.31
F11 P03951 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28845961 0.74 LPL (0.43) LPLLIPG
SCHEMBL18173799 0.71 HDAC8 (0.41) LPLLIPG
SCHEMBL24141578 0.71 LPL (0.38) LPLLIPGP2RX7CA1CA2
SCHEMBL19885232 0.70 LPL (0.41) LPLLIPGP2RX7CA1CA2
SCHEMBL19887482 0.70 LPL (0.33) LPLLIPG
SCHEMBL18092375 0.68 LIPG (0.37) LPLLIPGJAK2BTKP2RX7
SCHEMBL23089229 0.68 JAK2 (0.41) LPLLIPGJAK2BTK
SCHEMBL23104647 0.67 CDK8 (0.41) LPLLIPGP2RX7
SCHEMBL860007 0.67 BUB1 (0.40) F11
SCHEMBL21630705 0.66 LPL (0.35) LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11721838-B2 Electrolyte and electrochemical apparatus NINGDE AMPEREX TECHNOLOGY LIMITED (CN) 2023-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11721838-B2 Electrolyte and electrochemical apparatus HCN2, HCN3, KCNH3 LPL 4442/4885LIPG 4064/4885JAK2 2252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.