Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | LPL | P06858 | 3/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.38 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16907891 | 0.81 | BRD4 (0.47) | ALDH1A1KDM4EL3MBTL1BRD4BRD2 | |
| SCHEMBL3281005 | 0.79 | CYP11B2 (0.49) | LPLLIPGANPEPLAP3DGAT1 | |
| SCHEMBL19260099 | 0.74 | P2RX7 (0.41) | ALDH1A1KDM4ELPLLIPGL3MBTL1 | |
| SCHEMBL19887482 | 0.74 | LPL (0.33) | ALDH1A1LPLLIPG | |
| SCHEMBL3288256 | 0.73 | MAPK14 (0.47) | HDAC6KDM4ELPLLIPGELANE | |
| SCHEMBL28845961 | 0.72 | LPL (0.43) | ALDH1A1LPLLIPGANPEPLAP3 | |
| SCHEMBL14857772 | 0.71 | LIPG (0.46) | LPLLIPGANPEPLAP3ELANE | |
| SCHEMBL18239357 | 0.71 | HTR6 (0.48) | LPLLIPGBRD4DGAT1 | |
| SCHEMBL2240402 | 0.71 | APP (0.44) | HDAC8HDAC6LPLLIPGBRD4 | |
| SCHEMBL30717 | 0.71 | LPL (0.40) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10821429-B2 | Precatalysts and process for the metal-free functionalization of SP2 carbons using the same | UNIVERSITé LAVAL (CA) | 2020-11-03 | — | — | US | disclosed |
| US-20190262817-A1 | PRECATALYSTS AND PROCESS FOR THE METAL-FREE FUNCTIONALIZATION OF SP2 CARBONS USING THE SAME | UNIVERSITé LAVAL (CA) | 2019-08-29 | — | — | US | disclosed |
| US-10258976-B2 | Precatalysts and process for the metal-free functionalization of SP2 carbons using the same | UNIVERSITé LAVAL (CA) | 2019-04-16 | — | — | US | disclosed |
| EP-3389859-A1 | PRECATALYSTS AND PROCESS FOR THE METAL-FREE FUNCTIONALIZATION OF SP2 CARBONS USING THE SAME | Université Laval (CA) | 2018-10-24 | — | — | EP | disclosed |
| US-20180280950-A1 | PRECATALYSTS AND PROCESS FOR THE METAL-FREE FUNCTIONALIZATION OF SP2 CARBONS USING THE SAME | UNIVERSITE LAVAL (CA) | 2018-10-04 | — | — | US | disclosed |
| EP-3298018-A1 | PROCESS FOR THE FUNCTIONALIZATION OF SP2-H CARBONS USING FRUSTRATED LEWIS PAIR CATALYSTS. | Université Laval (CA) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016168914-A1 | PROCESS FOR THE FUNCTIONALIZATION OF SP2-H CARBONS USING FRUSTRATED LEWIS PAIR CATALYSTS | UNIVERSITé LAVAL (CA) | 2016-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10258976-B2 | Precatalysts and process for the metal-free functionalization of SP2 carbons using the same | SP1, LEF1, FOS | HDAC8 4024/4885HDAC6 1377/4885ALDH1A1 3228/4885 |
| US-20180280950-A1 | PRECATALYSTS AND PROCESS FOR THE METAL-FREE FUNCTIONALIZATION OF SP2 CARBONS USING THE SAME | SP1, LEF1, FOS | HDAC8 4024/4885HDAC6 1377/4885ALDH1A1 3228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.