Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.65 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | APEX1 | P27695 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30781973 | 1.00 | ADRB2 (0.65) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL29358069 | 0.86 | ADRB2 (0.76) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10840880 | 0.84 | ADRB2 (0.66) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL10839737 | 0.83 | CYP2D6 (0.74) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL13204416 | 0.82 | ADRB1 (0.78) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10840958 | 0.82 | MAPT (0.68) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| Bisoprolol SCHEMBL233810 | 0.79 | ADRB1 (1.00) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| Bisoprolol SCHEMBL6510329 | 0.79 | ADRB1 (1.00) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| Bisoprolol SCHEMBL20960 | 0.79 | ADRB1 (1.00) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| Bisoprolol SCHEMBL20961 | 0.79 | ADRB1 (1.00) | ADRB2ADRB1ADRB3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111110854-A | Composition comprising a histamine release-promoting substance and an inhibitory compound | 黄泳华 | 2020-05-08 | — | — | CN | claimed |
| CN-111110854-A | Composition comprising a histamine release-promoting substance and an inhibitory compound | 黄泳华 | 2020-05-08 | — | — | CN | disclosed |
| EP-2857014-B1 | A pharmaceutical composition comprising aspirin and bisoprolol | CAL INTERNAT LTD (IE) | 2016-06-22 | — | — | EP | disclosed |
| EP-2857014-A1 | A pharmaceutical composition comprising aspirin and bisoprolol | CAL INTERNATIONAL LIMITED (IE) | 2015-04-08 | — | — | EP | disclosed |
| EP-2566472-B1 | A PHARMACEUTICAL COMPOSITION COMPRISING ASPIRIN AND BISOPROLOL | CAL INTERNAT LTD (IE) | 2015-01-07 | — | — | EP | disclosed |
| EP-2566472-A1 | A PHARMACEUTICAL COMPOSITION COMPRISING ASPIRIN AND BISOPROLOL | CAL INTERNATIONAL LIMITED (IE) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011138772-A1 | A PHARMACEUTICAL COMPOSITION COMPRISING ASPIRIN AND BISOPROLOL | CAL INTERNATIONAL LIMITED (IE) | 2011-11-10 | — | — | WO | disclosed |