Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25938744 | 0.87 | MTNR1A (0.43) | MTNR1AMTNR1BKDM4ERENMAP3K14 | |
| SCHEMBL25942293 | 0.86 | MTNR1A (0.43) | MTNR1AMTNR1BKDM4ERENHPGD | |
| SCHEMBL25942292 | 0.79 | MTNR1A (0.38) | MTNR1AMTNR1BKDM4ERENHPGD | |
| SCHEMBL26184766 | 0.77 | SMN1; SMN2 (0.39) | KDM4EHPGDPOLBSMN1; SMN2PDE4B | |
| SCHEMBL25938395 | 0.76 | SMN1; SMN2 (0.40) | MTNR1AMTNR1BKDM4EHPGDPOLB | |
| SCHEMBL25948520 | 0.74 | MAPT (0.40) | MTNR1AKDM4EHPGDPOLBSMN1; SMN2 | |
| SCHEMBL25940711 | 0.71 | ALOX5 (0.44) | MTNR1AKDM4EHPGDPOLBSMN1; SMN2 | |
| SCHEMBL21979493 | 0.70 | MTNR1A (0.42) | MTNR1AMTNR1BKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL25940696 | 0.70 | SMN1; SMN2 (0.53) | KDM4EHPGDPOLBSMN1; SMN2PDE4D | |
| SCHEMBL8136831 | 0.66 | MTNR1A (0.56) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |