Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.38 |
| ▸ | PTPRF | P10586 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPRA | P18433 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22833101 | 0.80 | DAO (0.43) | ALDH1A1GPR35GSK3BTSHRMAPT | |
| SCHEMBL861808 | 0.76 | GPR35 (0.38) | GPR35GSK3BTSHRCYP2C9 | |
| SCHEMBL16901854 | 0.70 | ALDH1A1 (0.30) | ALDH1A1HPGD | |
| SCHEMBL3780362 | 0.70 | GPR35 (0.48) | ALDH1A1GPR35GSK3BMAPTLMNA | |
| SCHEMBL18067936 | 0.69 | USP2 (0.41) | ALDH1A1HPGDL3MBTL1LMNA | |
| SCHEMBL15878596 | 0.69 | GSK3B (0.61) | GPR35GSK3BPOLBAKR1C3 | |
| SCHEMBL17227588 | 0.68 | RAF1 (0.42) | ALDH1A1HPGDGSK3BFEN1TSHR | |
| SCHEMBL27708565 | 0.68 | AGTR2 (0.31) | — | |
| SCHEMBL31261454 | 0.67 | MME (0.38) | ALDH1A1HPGD | |
| SCHEMBL31261458 | 0.67 | MME (0.38) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133271-A1 | BICYCLIC PHTHALAZIN-1(2H)-ONE DERIVATIVES AND RELATED USES | NodThera Limited (GB) | 2023-07-13 | — | — | WO | disclosed |