Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 13/20 | 0.44 |
| ▸ | THRA | P10827 | 12/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25949891 | 0.85 | THRB (0.50) | THRBTHRAGABRA1GABRB1LMNA | |
| SCHEMBL25950328 | 0.84 | THRB (0.46) | THRBTHRAGABRA1LMNAS1PR1 | |
| SCHEMBL25926148 | 0.84 | THRB (0.43) | THRBTHRALMNA | |
| SCHEMBL24132695 | 0.84 | THRA (0.62) | THRBTHRAGABRA1GABRB1LMNA | |
| SCHEMBL25949903 | 0.81 | THRB (0.44) | THRBTHRA | |
| SCHEMBL26997448 | 0.79 | THRB (0.51) | THRBTHRA | |
| SCHEMBL24132159 | 0.77 | THRB (0.41) | THRBTHRACCR2CCR5 | |
| SCHEMBL10105497 | 0.75 | THRB (0.49) | THRBTHRA | |
| SCHEMBL10105507 | 0.73 | THRB (0.47) | THRBTHRA | |
| SCHEMBL25983465 | 0.73 | THRB (0.53) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242471-A1 | THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242471-A1 | THYROMIMETICS | TPO, THOP1, THRB | THRB 3/4885THRA 6/4885GABRA1 2935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.