Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 3/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2593275 | 0.83 | CRHBP (0.54) | KMT2AL3MBTL1ALDH1A1MEN1LMNA | |
| SCHEMBL2595555 | 0.82 | NR1D1 (0.43) | KMT2AL3MBTL1ALDH1A1MEN1LMNA | |
| SCHEMBL5703802 | 0.81 | KMT2A (0.48) | KMT2AL3MBTL1ALDH1A1MEN1LMNA | |
| SCHEMBL9823156 | 0.80 | HDAC1 (0.54) | KMT2AL3MBTL1MEN1LMNAHDAC1 | |
| SCHEMBL16468408 | 0.79 | ALDH1A1 (0.51) | KMT2AL3MBTL1ALDH1A1MEN1LMNA | |
| SCHEMBL579800 | 0.78 | ALDH1A1 (0.52) | KMT2AL3MBTL1ALDH1A1MEN1LMNA | |
| SCHEMBL4584322 | 0.78 | L3MBTL1 (0.49) | KMT2AL3MBTL1ALDH1A1MEN1LMNA | |
| SCHEMBL16682344 | 0.78 | KCNH2 (0.53) | KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15498153 | 0.78 | ALDH1A1 (0.42) | KMT2AALDH1A1MEN1LMNAHDAC1 | |
| SCHEMBL6377823 | 0.78 | ALDH1A1 (0.48) | KMT2AL3MBTL1ALDH1A1HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141716-A2 | PHARMACEUTICAL COMPOUNDS | SENTINEL ONCOLOGY LIMITED (GB) | 2011-11-17 | — | — | WO | disclosed |