Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 4/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25958653 | 0.84 | ALDH1A1 (0.42) | CNR2ALDH1A1HPGDKMT2A | |
| SCHEMBL25958758 | 0.81 | ALOX5AP (0.38) | TRPC6 | |
| SCHEMBL25958544 | 0.80 | VNN1 (0.39) | SCN9AVNN1TRPC6MTORPIK3CA | |
| SCHEMBL25959270 | 0.79 | SCN9A (0.40) | SCN9AVNN1MTORPIK3CACYP3A4 | |
| SCHEMBL25958662 | 0.78 | SMN1; SMN2 (0.45) | VNN1HSD17B10ALDH1A1HPGD | |
| SCHEMBL25958835 | 0.77 | SCN9A (0.38) | SCN9ATRPC6 | |
| SCHEMBL25958820 | 0.75 | SMN1; SMN2 (0.36) | HPGD | |
| SCHEMBL25958792 | 0.72 | VNN1 (0.40) | VNN1HPGDKMT2A | |
| SCHEMBL25958722 | 0.72 | DPP4 (0.31) | F11 | |
| SCHEMBL13388369 | 0.70 | ALDH1A1 (0.46) | SCN9AVNN1HIF1ACYP3A4USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3870582-B1 | 5-AZAINDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2023-07-19 | — | — | EP | disclosed |