Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25958662 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2HPGDTSHRESR2GRM5 | |
| SCHEMBL25958792 | 0.77 | VNN1 (0.40) | SMN1; SMN2HPGDTSHRESR2GRM5 | |
| SCHEMBL25958653 | 0.75 | ALDH1A1 (0.42) | HPGDTSHRNPC1RAB9A | |
| SCHEMBL25958773 | 0.75 | SCN9A (0.36) | HPGD | |
| SCHEMBL25959308 | 0.73 | LRRK2 (0.36) | SMN1; SMN2HPGDTSHRESR2PDE4B | |
| SCHEMBL25958568 | 0.73 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDTSHRESR2GRM5 | |
| SCHEMBL25958758 | 0.72 | ALOX5AP (0.38) | — | |
| SCHEMBL25958835 | 0.69 | SCN9A (0.38) | — | |
| SCHEMBL25958722 | 0.65 | DPP4 (0.31) | — | |
| SCHEMBL24058910 | 0.63 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDTSHRESR2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3870582-B1 | 5-AZAINDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2023-07-19 | — | — | EP | disclosed |