Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | TRPC6 | Q9Y210 | 9/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.36 |
| ▸ | FEN1 | P39748 | 3/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25958758 | 0.95 | ALOX5AP (0.38) | TRPC6ALOX5APFEN1L3MBTL3L3MBTL1 | |
| SCHEMBL25958653 | 0.87 | ALDH1A1 (0.42) | L3MBTL3L3MBTL1CNR1PTK2DPP4 | |
| SCHEMBL25958662 | 0.81 | SMN1; SMN2 (0.45) | ALOX5APFEN1HTR2C | |
| SCHEMBL25958594 | 0.81 | SCN9A (0.40) | SCN9ATRPC6L3MBTL3L3MBTL1PCSK9 | |
| SCHEMBL25959315 | 0.79 | SCN9A (0.41) | SCN9AALOX5APFEN1L3MBTL3L3MBTL1 | |
| SCHEMBL25958792 | 0.77 | VNN1 (0.40) | ALOX5APFEN1DPP4 | |
| SCHEMBL25958773 | 0.77 | SCN9A (0.36) | SCN9ATRPC6 | |
| SCHEMBL25958496 | 0.75 | TRPC6 (0.39) | SCN9ATRPC6L3MBTL3L3MBTL1PCSK9 | |
| SCHEMBL25959229 | 0.74 | PCSK9 (0.39) | SCN9ATRPC6ALOX5APFEN1PCSK9 | |
| SCHEMBL25958516 | 0.72 | TRPC6 (0.38) | SCN9ATRPC6ALOX5APFEN1L3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3870582-B1 | 5-AZAINDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2023-07-19 | — | — | EP | disclosed |