Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CTH | P32929 | 1/20 | 0.32 |
| ▸ | CBS | P35520 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684412 | 0.96 | CA4 (0.42) | CA4TSHRCTHCBSTHPO | |
| SCHEMBL9748913 | 0.96 | CA4 (0.42) | CA4TSHRCTHCBSTHPO | |
| SCHEMBL4323705 | 0.84 | TSHR (0.39) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL4323713 | 0.81 | LDHA (0.40) | TSHRCTHCBSTHPOTHRB | |
| Potassium Ion SCHEMBL11542915 | 0.81 | CA1 (0.32) | TSHRCTHCBSTHPOTHRB | |
| Potassium Ion SCHEMBL11544049 | 0.81 | CA1 (0.32) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL11684398 | 0.79 | LDHA (0.38) | TSHRCTHCBSTHPOTHRB | |
| Potassium Ion SCHEMBL11743473 | 0.79 | CA1 (0.34) | TSHRCTHCBSTHPO | |
| Potassium Ion SCHEMBL11742623 | 0.79 | CA1 (0.34) | TSHRCTHCBSTHPO | |
| SCHEMBL11393564 | 0.77 | CA1 (0.32) | TSHRCTHCBSTHPOTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9464261-B2 | Polymer-containing cleaning compositions and methods of production and use thereof | THE SUN PRODUCTS CORPORATION (US) | 2016-10-11 | — | — | US | disclosed |
| EP-2569406-A1 | POLYMER-CONTAINING CLEANING COMPOSITIONS AND METHODS OF PRODUCTION AND USE THEREOF | The Sun Products Corporation (US) | 2013-03-20 | — | — | EP | disclosed |
| US-20120122747-A1 | POLYMER-CONTAINING CLEANING COMPOSITIONS AND METHODS OF PRODUCTION AND USE THEREOF | THE SUN PRODUCTS CORPORATION (US) | 2012-05-17 | — | — | US | disclosed |
| WO-2011143602-A1 | POLYMER-CONTAINING CLEANING COMPOSITIONS AND METHODS OF PRODUCTION AND USE THEREOF | THE SUN PRODUCTS CORPORATION (US) | 2011-11-17 | — | — | WO | disclosed |
| EP-1003828-A1 | DETERGENT COMPOSITIONS CONTAINING POLYETHYLENEIMINES FOR ENHANCED STAIN REMOVAL | UNILEVER PLC (GB) | 2000-05-31 | — | — | EP | disclosed |
| US-5904735-A | Detergent compositions containing polyethyleneimines for enhanced stain removal | LEVER BROTHERS COMPANY (US) | 1999-05-18 | — | — | US | disclosed |
| WO-1999007815-A1 | DETERGENT COMPOSITIONS CONTAINING POLYETHYLENEIMINES FOR ENHANCED STAIN REMOVAL | UNILEVER PLC (GB) | 1999-02-18 | — | — | WO | disclosed |
| US-5750733-A | Hydroxy containing alkyl glycamides, low foaming detergent compositions comprising such and a process for their manufacture | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1998-05-12 | — | — | US | disclosed |
| WO-1997034984-A1 | DETERGENT COMPOSITIONS CONTAINING DIAMINOALKYL DISULPHOSUCCINATED SEQUESTRANTS | UNILEVER PLC (GB) | 1997-09-25 | — | — | WO | disclosed |