Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GALR3 | O60755 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SELL | P14151 | 1/20 | 0.48 |
| ▸ | SELP | P16109 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516248 | 0.78 | HPGD (1.00) | HPGDPOLBHTTRAB9ASMN1; SMN2 | |
| SCHEMBL28021805 | 0.76 | LMNA (0.74) | HPGDPOLBHTTRAB9ASMN1; SMN2 | |
| SCHEMBL24254523 | 0.74 | HPGD (0.59) | HPGDPOLBGALR3HTTRAB9A | |
| SCHEMBL11307527 | 0.73 | HPGD (0.63) | HPGDPOLBGALR3HTTRAB9A | |
| SCHEMBL24254500 | 0.73 | ALDH1A1 (0.78) | HPGDRAB9ASMN1; SMN2LMNATHRB | |
| SCHEMBL12700241 | 0.72 | HPGD (0.70) | HPGDRAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL3539902 | 0.71 | PDK1 (0.40) | HTTSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL6918329 | 0.71 | POLB (0.67) | HPGDPOLBRAB9ASMN1; SMN2LMNA | |
| SCHEMBL13536561 | 0.71 | HPGD (0.79) | HPGDPOLBSMN1; SMN2LMNATP53 | |
| SCHEMBL29246708 | 0.70 | HPGD (0.68) | HPGDPOLBGALR3HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3421454-B9 | PIPERIDINE DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2023-08-09 | — | — | EP | disclosed |