Sugi Predict

Sugi Predict / Compounds / SCHEMBL553299

SCHEMBL553299

SCHEMBL553299

CN(CCO)C(=O)OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.53
▸ CCR6 P51684 1/20 0.50
▸ PAX8 Q06710 1/20 0.50
▸ MAPT P10636 1/20 0.49
▸ HPGD P15428 1/20 0.49
▸ F13A1 P00488 1/20 0.48
▸ TGM2 P21980 1/20 0.48
▸ TGM1 P22735 1/20 0.48
▸ MAPK1 P28482 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ SLC6A2 P23975 1/20 0.47
▸ SLC6A3 Q01959 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ TDP1 Q9NUW8 1/20 0.47
▸ SIGMAR1 Q99720 1/20 0.45
▸ ABCB1 P08183 1/20 0.45
▸ HDAC1 Q13547 1/20 0.45
▸ CHRNB2 P17787 2/20 0.44
▸ CHRNB4 P30926 2/20 0.44
▸ CHRNA3 P32297 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5722156 0.93 ALDH1A1 (0.63) ALDH1A1CCR6PAX8MAPTHPGD
SCHEMBL7367495 0.91 ALDH1A1 (0.58) ALDH1A1CCR6PAX8MAPTHPGD
SCHEMBL5028497 0.91 ALDH1A1 (0.47) ALDH1A1CCR6PAX8MAPTHPGD
SCHEMBL1897393 0.90 CCR6 (0.51) ALDH1A1CCR6PAX8MAPTHPGD
SCHEMBL19346032 0.89 CCR6 (0.53) ALDH1A1CCR6PAX8MAPTHPGD
SCHEMBL31473983 0.89 ALDH1A1 (0.49) ALDH1A1CCR6PAX8MAPTHPGD
SCHEMBL3170360 0.88 CCR6 (0.52) ALDH1A1CCR6PAX8MAPTHPGD
SCHEMBL8424282 0.88 CCR6 (0.52) ALDH1A1CCR6PAX8MAPTHPGD
SCHEMBL31474078 0.87 ALDH1A1 (0.50) ALDH1A1CCR6PAX8MAPTHPGD
SCHEMBL5030213 0.87 F13A1 (0.45) ALDH1A1CCR6PAX8MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4701666-A1 ANTIBODY-DRUG CONJUGATE COMPOUNDS, AND METHODS OF USE AND TREATMENT Iksuda Therapeutics Limited (GB) 2026-03-04 — — EP disclosed
US-20250388615-A9 SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS ARDELYX, INC. (US) 2025-12-25 — — US disclosed
US-20250066410-A1 SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS ARDELYX, INC. (US) 2025-02-27 — — US disclosed
US-20250034200-A1 Prodrugs of Neurosteroid Analogs and Uses Thereof UNIV EMORY (US) 2025-01-30 — — US disclosed
US-20240425512-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND APPLICATION THEREOF 280 BIO, INC. (US) 2024-12-26 — — US disclosed
WO-2024254404-A2 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND APPLICATION THEREOF 280 BIO, INC. (US) 2024-12-12 — — WO disclosed
CN-119101070-A Nitrogen-containing heterocyclic compound, pharmaceutical composition and application thereof 上海璎黎药业有限公司 2024-12-10 — — CN disclosed
WO-2024224112-A1 ANTIBODY-DRUG CONJUGATE COMPOUNDS, AND METHODS OF USE AND TREATMENT Iksuda Therapeutics Limited (GB) 2024-10-31 — — WO disclosed
US-12084472-B2 Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists ARDELYX, INC. (US) 2024-09-10 — — US disclosed
US-12054461-B2 Sulfonylurea derivatives and uses thereof NodThera Limited (GB) 2024-08-06 — — US disclosed
WO-1992007838-A1 THIAZOLIDINE DIONE DERIVATIVES BEECHAM GROUP PLC (GB) 1992-05-14 — — WO disclosed
US-5059589-A Glaucoma treatment ABBOTT LABORATORIES (US) 1991-10-22 — — US disclosed
EP-0415981-A4 RETROVIRAL PROTEASE INHIBITORS — 1991-10-09 — — EP disclosed
EP-0415981-A1 RETROVIRAL PROTEASE INHIBITORS ABBOTT LABORATORIES (US) 1991-03-13 — — EP disclosed
EP-0402646-A1 Retroviral protease inhibiting compounds ABBOTT LABORATORIES (US) 1990-12-19 — — EP disclosed
EP-0342541-A2 Retroviral protease inhibitors ABBOTT LABORATORIES (US) 1989-11-23 — — EP disclosed
WO-1989010752-A1 RETROVIRAL PROTEASE INHIBITORS ABBOTT LABORATORIES (US) 1989-11-16 — — WO disclosed
EP-0107120-B1 SUBSTITUTED AMINOALCANOL PHOSPHOLIPIDS AND PROCESS FOR THEIR PREPARATION A. Nattermann & Cie. GmbH (DE) 1986-10-29 — — EP disclosed
US-4565659-A Substituted aminoalkanol phospholipids A. NATTERMANN & CIE GMBH (DE) 1986-01-21 — — US disclosed
EP-0107120-A1 Substituted aminoalcanol phospholipids and process for their preparation A. Nattermann & Cie. GmbH (DE) 1984-05-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250066410-A1 SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS GPR119, GIPR, GLP1R ALDH1A1 4357/4885CCR6 589/4885PAX8 2874/4885
US-20250388615-A9 SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS GPR119, GIPR, FFAR3 ALDH1A1 3776/4885CCR6 57/4885PAX8 2145/4885
US-12054461-B2 Sulfonylurea derivatives and uses thereof IL1B, NOD1, IL1A ALDH1A1 188/4885CCR6 1837/4885PAX8 2697/4885
US-20250034200-A1 Prodrugs of Neurosteroid Analogs and Uses Thereof CYP11B2, CYP11B1, CYP21A2 ALDH1A1 645/4885CCR6 3184/4885PAX8 4233/4885
US-20240425512-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND APPLICATION THEREOF KRAS, NRAS, HRAS ALDH1A1 2559/4885CCR6 2324/4885PAX8 2704/4885
US-12084472-B2 Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists GPR119, GIPR, GLP1R ALDH1A1 4357/4885CCR6 589/4885PAX8 2874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.