Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9051809 | 0.87 | ALDH1A1 (0.61) | ALDH1A1TDP1RAB9ARECQLNPC1 | |
| SCHEMBL3182861 | 0.86 | CA1 (0.55) | ALDH1A1TDP1RAB9ARECQLNPC1 | |
| SCHEMBL9367346 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TDP1RAB9ARECQLNPC1 | |
| SCHEMBL11259237 | 0.82 | ALDH1A1 (0.56) | ALDH1A1TDP1RAB9ARECQLNPC1 | |
| SCHEMBL9316440 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TDP1RAB9ARECQLNPC1 | |
| SCHEMBL3921718 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TDP1RAB9ARECQLNPC1 | |
| SCHEMBL27749820 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TDP1RAB9ARECQLNPC1 | |
| SCHEMBL11670654 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TDP1RAB9ARECQLNPC1 | |
| SCHEMBL1276317 | 0.79 | RAB9A (0.45) | ALDH1A1TDP1RAB9ARECQLNPC1 | |
| SCHEMBL2596745 | 0.79 | ALDH1A1 (0.51) | ALDH1A1TDP1RAB9ARECQLNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2568807-B1 | PHENOXYALKYL PYRIDINIUM OXIME THERAPEUTICS FOR TREATMENT OF ORGANOPHOSPHATE POISONING | UNIV MISSISSIPPI STATE (US) | 2018-07-11 | — | — | EP | disclosed |
| US-20170258774-A1 | NOVEL OXIMES FOR REACTIVATING BUTYRYLCHOLINESTERASE | MISSISSIPPI STATE UNIVERSITY (US) | 2017-09-14 | — | — | US | disclosed |
| US-9227937-B2 | Phenoxyalkyl pyridinium oxime therapeutics for treatment of organophosphate poisoning | MISSISSIPPI STATE UNIVERSITY (US) | 2016-01-05 | — | — | US | disclosed |
| US-20130172393-A1 | PHENOXYALKYL PYRIDINIUM OXIME THERAPEUTICS FOR TREATMENT OF ORGANOPHOSPHATE POISONING | MISSISSIPPI STATE UNIVERSITY | 2013-07-04 | — | — | US | disclosed |
| EP-2568807-A1 | PHENOXYALKYL PYRIDINIUM OXIME THERAPEUTICS FOR TREATMENT OF ORGANOPHOSPHATE POISONING | Mississipi State University (US) | 2013-03-20 | — | — | EP | disclosed |
| WO-2011142826-A1 | PHENOXYALKYL PYRIDINIUM OXIME THERAPEUTICS FOR TREATMENT OF ORGANOPHOSPHATE POISONING | MISSISSIPI STATE UNIVERSITY (US) | 2011-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172393-A1 | PHENOXYALKYL PYRIDINIUM OXIME THERAPEUTICS FOR TREATMENT OF ORGANOPHOSPHATE POISONING | PNPO, PLPBP, PDXK | ALDH1A1 2536/4885TDP1 589/4885RAB9A 4146/4885 |
| US-20170258774-A1 | NOVEL OXIMES FOR REACTIVATING BUTYRYLCHOLINESTERASE | BCHE, ACHE, CHAT | ALDH1A1 1183/4885TDP1 315/4885RAB9A 1917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.