Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 4/20 | 0.35 |
| ▸ | BACE1 | P56817 | 3/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL199860 | 0.87 | SHBG (0.47) | SHBGCYP3A4SMN1; SMN2BACE1IDH1 | |
| SCHEMBL30038339 | 0.83 | SHBG (0.41) | SHBGCYP3A4SMN1; SMN2BACE1IDH1 | |
| SCHEMBL27169618 | 0.83 | SHBG (0.41) | SHBGCYP3A4SMN1; SMN2BACE1IDH1 | |
| SCHEMBL28249286 | 0.78 | CNR1 (0.42) | PTPN5CYP3A4BACE1 | |
| SCHEMBL1129606 | 0.78 | PTPN1 (0.55) | SHBG | |
| SCHEMBL28069366 | 0.77 | MAPK1 (0.43) | PTPN5CYP3A4SMN1; SMN2BACE1 | |
| SCHEMBL8990196 | 0.75 | SHBG (0.47) | SHBGCYP3A4SMN1; SMN2IDH1 | |
| SCHEMBL29538101 | 0.75 | CYP3A4 (0.49) | SHBGCYP3A4SMN1; SMN2BACE1 | |
| SCHEMBL647965 | 0.75 | CYP3A4 (0.49) | SHBGCYP3A4SMN1; SMN2BACE1 | |
| Zinc Ion SCHEMBL7088082 | 0.75 | PTPN1 (0.42) | SHBGPTGDR2CYP3A4SMN1; SMN2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011146044-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-11-24 | — | — | WO | claimed |
| EP-4244280-A1 | PREPARATION OF POLYOLEFIN-POLYACRYLATE BLOCK COPOLYMERS ADDITIVES FOR INCREASING SURFACE ENERGY OF POLYETHYLENE | Dow Global Technologies LLC (US) | 2023-09-20 | — | — | EP | disclosed |
| WO-2022103800-A1 | PREPARATION OF POLYOLEFIN-POLYACRYLATE BLOCK COPOLYMERS ADDITIVES FOR INCREASING SURFACE ENERGY OF POLYETHYLENE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-05-19 | — | — | WO | disclosed |