SCHEMBL25968649

SCHEMBL25968649

Cc1ccc(-c2ccc(C(C(C)C)C(C)C)c[n+]2C)c(C)c1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25445895 0.88 LMNA (0.42) LMNAGAAMAPT
SCHEMBL25445584 0.80 MAPT (0.38) LMNAGAAMAPT
SCHEMBL25450348 0.78 LMNA (0.46) LMNA
SCHEMBL25450505 0.78 LMNA (0.48) LMNAGAA
SCHEMBL25445902 0.75 LMNA (0.37) LMNAGAAMAPT
SCHEMBL25445901 0.75 LMNA (0.37) LMNAGAAMAPT
SCHEMBL25445920 0.75 KDM4E (0.33) GAAMAPT
SCHEMBL25968618 0.73 AKR1C3 (0.33) LMNA
SCHEMBL25445936 0.72 TSHR (0.39) LMNAGAAMAPT
SCHEMBL25451688 0.72 LMNA (0.37) LMNAGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209990-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230209990-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L3MBTL3, AGO2, ELAVL3 LMNA 94/4885GAA 3329/4885MAPT 3793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.