SCHEMBL25445936

SCHEMBL25445936

Cc1ccc(-c2ccc(C(C)(C)C)c[n+]2C)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
POLB P06746 1/20 0.32
HSD17B2 P37059 3/20 0.32
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
NPC1 O15118 1/20 0.31
PLA2G1B P04054 1/20 0.31
NFKB1 P19838 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ATG4B Q9Y4P1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25885896 0.92 ALDH1A1 (0.37) TSHRGAAMAPTPOLBALDH1A1
SCHEMBL25450386 0.89 TSHR (0.41) TSHRGAAMAPTHSD17B2ALDH1A1
SCHEMBL26571130 0.87 TSHR (0.39) TSHRMAPTPOLBHSD17B2ALDH1A1
SCHEMBL26023976 0.86 KIF11 (0.38) MAPT
SCHEMBL25445963 0.85 CNR1 (0.33) CNR1CNR2
SCHEMBL25445978 0.85 MAPK1 (0.37) MAPTLMNANPC1CASP3RAB9A
SCHEMBL26023939 0.84 MAPT (0.36) GAAMAPTALDH1A1LMNANPC1
SCHEMBL26345105 0.84 SERPINE1 (0.35) POLBHSD17B2LMNANPC1CASP3
SCHEMBL25884430 0.83 CNR1 (0.31) GAAMAPTCNR1CNR2
SCHEMBL25445584 0.83 MAPT (0.38) GAAMAPTALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
EP-4329463-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2024-02-28 EP disclosed
EP-4001287-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2024-01-17 EP disclosed
US-11864458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-01-02 US disclosed
US-11839141-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
EP-3858945-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-11-29 EP disclosed
US-11827651-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230151039-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-18 US disclosed
US-20230157154-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-18 US disclosed
EP-3771717-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-05-17 EP disclosed
US-20230143449-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-20230142498-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-20230147066-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-20230146148-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-11647667-B2 Organic electroluminescent compounds and organic light emitting devices using the same UNIVERSAL DISPLAY CORPORATION (US) 2023-05-09 US disclosed
US-11639363-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-05-02 US disclosed
US-20230130017-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157154-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, GLRA3 TSHR 124/4885GAA 3241/4885MAPT 3698/4885
US-20230146148-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ICOSLG TSHR 2227/4885GAA 1073/4885MAPT 1448/4885
US-11647667-B2 Organic electroluminescent compounds and organic light emitting devices using the same OCIAD1, OCIAD2, ODC1 TSHR 3962/4885GAA 2083/4885MAPT 587/4885
US-20230130017-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, SSB TSHR 2474/4885GAA 2772/4885MAPT 3388/4885
US-11839141-B2 Organic electroluminescent materials and devices OSBP, OCIAD1, OCIAD2 TSHR 2916/4885GAA 506/4885MAPT 2267/4885
US-11864458-B2 Organic electroluminescent materials and devices RAP1A, L1CAM, SOD1 TSHR 939/4885GAA 3779/4885MAPT 3446/4885
US-20230147066-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, SSB, MCOLN3 TSHR 1367/4885GAA 4338/4885MAPT 3411/4885
US-20230143449-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OXER1 TSHR 670/4885GAA 3691/4885MAPT 4402/4885
US-20230142498-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, LEF1 TSHR 4057/4885GAA 3308/4885MAPT 3520/4885
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP TSHR 1042/4885GAA 2849/4885MAPT 1707/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG TSHR 2736/4885GAA 2848/4885MAPT 1653/4885
US-11639363-B2 Organic electroluminescent materials and devices LEF1, L1CAM, SSB TSHR 729/4885GAA 2915/4885MAPT 3566/4885
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, ROS1 TSHR 189/4885GAA 3564/4885MAPT 3599/4885
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, OXSR1 TSHR 159/4885GAA 3221/4885MAPT 4215/4885
US-11827651-B2 Organic electroluminescent materials and devices SSB, L1CAM, LEF1 TSHR 608/4885GAA 1487/4885MAPT 2286/4885
US-20230151039-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RPS4X, SOD1, CNKSR1 TSHR 447/4885GAA 3525/4885MAPT 3876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.