SCHEMBL25450505

SCHEMBL25450505

Cc1cc(C(C)C)ccc1-c1ccc(C(C)C)c[n+]1C

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
PTGS1 P23219 2/20 0.39
TRPA1 O75762 1/20 0.39
CACNA1C Q13936 1/20 0.39
AKR1C3 P42330 4/20 0.31
AKR1C2 P52895 4/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
ALOX12 P18054 1/20 0.31
HTT P42858 1/20 0.31
HIF1A Q16665 1/20 0.31
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25445895 0.90 LMNA (0.42) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL25450348 0.90 LMNA (0.46) LMNAPTGS1TRPA1CACNA1CAKR1C3
SCHEMBL25450544 0.88 LMNA (0.38) LMNAPTGS1TRPA1CACNA1C
SCHEMBL25450507 0.88 LMNA (0.38) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL25450508 0.86 LMNA (0.39) LMNAPTGS1TRPA1CACNA1CAKR1C3
SCHEMBL25450661 0.85 LMNA (0.47) LMNAPTGS1TRPA1CACNA1CAKR1C3
SCHEMBL25450448 0.85 LMNA (0.41) LMNAPTGS1TRPA1CACNA1CAKR1C3
SCHEMBL25884014 0.85 LMNA (0.41) LMNAPTGS1TRPA1CACNA1CAKR1C3
SCHEMBL25450500 0.85 LMNA (0.38) LMNAPTGS1TRPA1CACNA1CAKR1C3
SCHEMBL26013286 0.85 LMNA (0.41) LMNAPTGS1TRPA1CACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12022727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-06-25 US disclosed
US-20240025934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 US disclosed
US-11844267-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-12 US disclosed
US-11839142-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
US-11825734-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-21 US disclosed
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-11818946-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-14 US disclosed
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-11778897-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-03 US disclosed
US-11760770-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-19 US disclosed
US-11744141-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-29 US disclosed
US-20230270003-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-08-24 US disclosed
US-20230240130-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-07-27 US disclosed
EP-4206210-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-07-05 EP disclosed
US-20230203076-A1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2023-06-29 US disclosed
US-20230209990-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-29 US disclosed
US-11685756-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-27 US disclosed
US-11683981-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-20 US disclosed
US-11678565-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-13 US disclosed
US-11653558-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (19 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11685756-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OPRD1 LMNA 3673/4885PTGS1 3313/4885TRPA1 146/4885
US-11844267-B2 Organic electroluminescent materials and devices L1CAM, LEF1, EPCAM LMNA 553/4885PTGS1 2948/4885TRPA1 42/4885
US-20240025934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, RO60, LIFR LMNA 1122/4885PTGS1 3790/4885TRPA1 1711/4885
US-11825734-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP LMNA 3477/4885PTGS1 3512/4885TRPA1 71/4885
US-11818946-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, AOC3 LMNA 572/4885PTGS1 3636/4885TRPA1 590/4885
US-11778897-B2 Organic electroluminescent materials and devices LIFR, LBR, ZFR LMNA 1222/4885PTGS1 4310/4885TRPA1 1180/4885
US-20230240130-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBPL3, LBR, RBM3 LMNA 338/4885PTGS1 2869/4885TRPA1 966/4885
US-20230270003-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, CHRM1, OSBPL8 LMNA 648/4885PTGS1 3024/4885TRPA1 1017/4885
US-11678565-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OPRD1 LMNA 782/4885PTGS1 1035/4885TRPA1 269/4885
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 LMNA 2182/4885PTGS1 3202/4885TRPA1 694/4885
US-11760770-B2 Organic electroluminescent materials and devices LEF1, L1CAM, AP1M1 LMNA 1144/4885PTGS1 3257/4885TRPA1 1350/4885
US-12022727-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 LMNA 1193/4885PTGS1 1506/4885TRPA1 123/4885
US-11744141-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, LBR LMNA 877/4885PTGS1 3986/4885TRPA1 66/4885
US-11683981-B2 Organic electroluminescent materials and devices OXER1, CHRM1, OSBPL8 LMNA 648/4885PTGS1 3024/4885TRPA1 1017/4885
US-20230209990-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L3MBTL3, AGO2, ELAVL3 LMNA 94/4885PTGS1 3398/4885TRPA1 332/4885
US-20230203076-A1 Organic electroluminescent materials and devices SSB, ADORA3, SNRPA1 LMNA 266/4885PTGS1 4076/4885TRPA1 784/4885
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, LBR, ZFR LMNA 1222/4885PTGS1 4310/4885TRPA1 1180/4885
US-11653558-B2 Organic electroluminescent materials and devices OSBPL3, LBR, LOXL3 LMNA 304/4885PTGS1 2411/4885TRPA1 839/4885
US-11839142-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OSBP LMNA 1980/4885PTGS1 2952/4885TRPA1 170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.