SCHEMBL18629181

SCHEMBL18629181

C=C/C=C\C(=C/C=C)OC(=O)Oc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.36
TGM2 P21980 1/20 0.35
KMT2A Q03164 3/20 0.33
MAOB P27338 2/20 0.33
ATM Q13315 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
HTT P42858 2/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
RAD51 Q06609 1/20 0.32
BCHE P06276 1/20 0.32
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18627721 0.88 ALDH1A1 (0.36) THRBTGM2KMT2AMAOBATM
SCHEMBL19244943 0.87 KMT2A (0.35) THRBTGM2KMT2AMAOBATM
SCHEMBL20153684 0.86 TGM2 (0.41) THRBTGM2KMT2AATMTDP1
SCHEMBL19558477 0.84 THRB (0.34) THRBTGM2KMT2AMAOBATM
SCHEMBL25969894 0.78 LMNA (0.41) KMT2ATDP1L3MBTL1ALDH1A1MAPT
SCHEMBL24317675 0.76 ALDH1A1 (0.36) KMT2AMAOBATMTDP1L3MBTL1
SCHEMBL21010421 0.76 ALDH1A1 (0.39) KMT2AATMTDP1L3MBTL1ALDH1A1
Butadiene SCHEMBL896449 0.74 TDP1 (0.45) THRBTGM2KMT2AATMTDP1
SCHEMBL18627661 0.74 MAOB (0.36) KMT2AMAOBATMTDP1L3MBTL1
SCHEMBL14597261 0.74 CA4 (0.37) THRBTGM2KMT2AMAOBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3571240-B1 REDUCED COLOR POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-08-30 EP disclosed
US-20220195114-A1 THERMOPLASTIC RESIN COMPOSITION AND FORMED PRODUCT MITSUBISHI CHEMICAL CORPORATION (JP) 2022-06-23 US disclosed
US-11312822-B2 Reduced color polycarbonate compositions, methods of manufacture, and articles thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-04-26 US disclosed
US-20220002540-A1 AROMATIC POLYCARBONATE RESIN COMPOSITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2022-01-06 US disclosed
US-20210292477-A1 REDUCED COLOR POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-09-23 US disclosed
US-20200048410-A1 SYNTHESIS OF A PHOSPHOROUS CONTAINING MONOMER AND THE INCORPORATION IN POLYCARBONATE BY INTERFACIAL POLYMERIZATION THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2020-02-13 US disclosed
US-10465061-B2 Polycarbonate composition to produce optical quality products with high quality and good processability SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-11-05 US disclosed
WO-2019048986-A1 METHOD FOR PRODUCING A POLYCARBONATE ARTICLE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-03-14 WO disclosed
WO-2018134734-A1 REDUCED COLOR POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-07-26 WO disclosed
US-20170233328-A1 METHOD OF MELT POLYMERIZING POLYCARBONATE AND THE POLYCARBONATE MADE THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-08-17 US disclosed
US-9732028-B2 Process for purification of diphenyl carbonate for the manufacturing of high quality polycarbonate SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-08-15 US disclosed
US-20170190871-A1 POLYCARBONATE COMPOSITION TO PRODUCE OPTICAL QUALITY PRODUCTS WITH HIGH QUALITY AND GOOD PROCESSABILITY SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2017-07-06 US disclosed
US-9644075-B2 Polycarbonate composition to produce optical quality products with high quality and good processability SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-05-09 US disclosed
WO-2017072676-A1 HIGH IMPACT POLYARYLETHERKETONE - POLYCARBONATE BLENDS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-05-04 WO disclosed
US-9617381-B2 Low shear process for polycarbonate purification SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-04-11 US disclosed
US-9617382-B2 Process for the purification of polycarbonate SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-04-11 US disclosed
US-9617380-B2 Thermal enhancement of the purification process for interfacial polycarbonate and copolymer polycarbonates SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-04-11 US disclosed
US-20170073299-A1 METHOD FOR PRODUCING DIARYL CARBONATES COVESTRO DEUTSCHLAND AG (DE) 2017-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170233328-A1 METHOD OF MELT POLYMERIZING POLYCARBONATE AND THE POLYCARBONATE MADE THEREFROM PHF2, CYP21A2, HSD11B2 THRB 4785/4885TGM2 3068/4885KMT2A 477/4885
US-20170073299-A1 METHOD FOR PRODUCING DIARYL CARBONATES ALPG, CYP21A2, PYGL THRB 4349/4885TGM2 2203/4885KMT2A 2702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.