Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 6/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | PLG | P00747 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CPT2 | P23786 | 2/20 | 0.37 |
| ▸ | CPT1A | P50416 | 2/20 | 0.37 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31565954 | 0.91 | NAMPT (0.44) | NAMPTESR1ESR2F10PLG | |
| SCHEMBL31565984 | 0.86 | CCR2 (0.44) | NAMPTESR1ESR2F10PLG | |
| SCHEMBL31566094 | 0.84 | ESR1 (0.43) | ESR1ESR2F10CCR2KCNH2 | |
| SCHEMBL3992628 | 0.79 | NAMPT (0.48) | NAMPTESR1ESR2F10KCNH2 | |
| SCHEMBL3998544 | 0.77 | CNR2 (0.48) | NAMPTF10CPT2CPT1AMOGAT2 | |
| SCHEMBL31565899 | 0.75 | LIPE (0.41) | NAMPTESR1ESR2F10SCN9A | |
| SCHEMBL31565889 | 0.75 | ESR1 (0.47) | ESR1ESR2 | |
| SCHEMBL31565989 | 0.74 | RORC (0.43) | NAMPTESR1ESR2F10 | |
| SCHEMBL31566005 | 0.74 | FAP (0.43) | NAMPTESR1ESR2F10KCNH2 | |
| SCHEMBL31566015 | 0.73 | CCR2 (0.46) | NAMPTESR1ESR2CCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147063-A2 | COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR | Opna Bio SA (CH) | 2023-08-03 | — | — | WO | disclosed |