Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | BRS3 | P32247 | 4/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 3/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3992628 | 0.86 | NAMPT (0.48) | FAPLIPEF10GHSRESR1 | |
| SCHEMBL31565903 | 0.84 | LIPE (0.42) | FAPLIPEESR1ESR2SCN7A | |
| SCHEMBL31565984 | 0.83 | CCR2 (0.44) | FAPLIPEF10ESR1ESR2 | |
| SCHEMBL31566094 | 0.83 | ESR1 (0.43) | FAPLIPEF10GHSRESR1 | |
| SCHEMBL31565899 | 0.82 | LIPE (0.41) | FAPLIPEBRS3F10GHSR | |
| SCHEMBL31565954 | 0.82 | NAMPT (0.44) | FAPLIPEF10ESR1ESR2 | |
| SCHEMBL31565879 | 0.81 | FAP (0.47) | FAPLIPEBRS3GHSRESR1 | |
| SCHEMBL31565989 | 0.81 | RORC (0.43) | FAPLIPEFAAHF10GHSR | |
| SCHEMBL31566103 | 0.80 | LIPE (0.42) | FAPLIPEGHSRESR1ESR2 | |
| SCHEMBL31566097 | 0.79 | FAP (0.47) | FAPLIPEBRS3GHSRESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129028-A1 | COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR | Opna Bio SA (CH) | 2025-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129028-A1 | COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR | YAP1, YES1, LATS1 | FAP 2858/4885LIPE 4593/4885BRS3 1048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.