Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | PITRM1 | Q5JRX3 | 3/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.35 |
| ▸ | FAP | Q12884 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17301107 | 0.78 | POLB (0.44) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL17414350 | 0.74 | KMT2A (0.34) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL13909534 | 0.73 | DPP4 (0.32) | DPP4DPP8DPP9DPP7POLB | |
| SCHEMBL15107202 | 0.73 | DPP4 (0.39) | DPP4PITRM1DPP8DPP9DPP7 | |
| SCHEMBL11990431 | 0.72 | DPP4 (0.33) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL11990408 | 0.72 | POLB (0.33) | DPP4DPP8DPP9DPP7POLB | |
| SCHEMBL11990433 | 0.69 | CHRNB2 (0.36) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL25970252 | 0.69 | L3MBTL1 (0.35) | DPP4PITRM1DPP8DPP9DPP7 | |
| SCHEMBL11990393 | 0.69 | DPP4 (0.33) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL13117947 | 0.68 | HTT (0.34) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | ALKBH1, DUT, RNGTT | DPP4 1352/4885PITRM1 3154/4885DPP8 860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.