Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17918626 | 1.00 | HSD11B1 (0.34) | HSD11B1ASGR1BTK | |
| SCHEMBL14690851 | 0.87 | BTK (0.41) | HSD11B1ASGR1BTK | |
| SCHEMBL30752581 | 0.87 | BTK (0.41) | HSD11B1ASGR1BTK | |
| SCHEMBL24062393 | 0.86 | HSD11B1 (0.39) | HSD11B1ASGR1BTK | |
| SCHEMBL25984544 | 0.84 | SLC6A2 (0.36) | HSD11B1ASGR1BTK | |
| SCHEMBL765452 | 0.83 | HSD11B1 (0.39) | HSD11B1ASGR1BTK | |
| SCHEMBL12807337 | 0.81 | HSD11B1 (0.36) | HSD11B1ASGR1BTK | |
| SCHEMBL7025154 | 0.81 | NFKB1 (0.40) | HSD11B1ASGR1 | |
| SCHEMBL12734555 | 0.80 | ASGR1 (0.37) | HSD11B1ASGR1BTK | |
| SCHEMBL12734461 | 0.80 | ASGR1 (0.37) | HSD11B1ASGR1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | ALKBH1, DUT, RNGTT | HSD11B1 4388/4885ASGR1 2944/4885BTK 3405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.