Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17138280 | 0.73 | SLC18A3 (0.48) | L3MBTL1SLC18A3MEN1KMT2ASLC6A2 | |
| SCHEMBL17138281 | 0.73 | SLC18A3 (0.48) | L3MBTL1SLC18A3MEN1KMT2ASLC6A2 | |
| SCHEMBL17138261 | 0.71 | L3MBTL1 (0.51) | L3MBTL1SLC18A3MEN1KMT2ASLC6A2 | |
| SCHEMBL25663657 | 0.71 | SLC6A2 (0.40) | LMNAMEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL25663636 | 0.69 | SIGMAR1 (0.40) | LMNAMEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL17138274 | 0.69 | L3MBTL1 (0.45) | L3MBTL1SLC18A3MEN1KMT2ASLC6A2 | |
| SCHEMBL17138272 | 0.69 | L3MBTL1 (0.45) | L3MBTL1SLC18A3MEN1KMT2ASLC6A2 | |
| SCHEMBL17138279 | 0.68 | L3MBTL1 (0.44) | L3MBTL1SLC18A3MEN1KMT2ASLC6A2 | |
| SCHEMBL18079511 | 0.67 | L3MBTL1 (0.46) | L3MBTL1SLC18A3MEN1KMT2ASLC6A2 | |
| SCHEMBL14492358 | 0.67 | SLC6A2 (0.56) | L3MBTL1SLC18A3MEN1KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | ALKBH1, DUT, RNGTT | L3MBTL1 1497/4885SLC18A3 2260/4885LMNA 434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.