SCHEMBL25972743

SCHEMBL25972743

c1ccc(-n2c3ccccc3c3cc(-c4cccc5cccc(-c6ccc7c(c6)c6ccccc6n7-c6ccc7ccccc7c6)c45)ccc32)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.45
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
HPGD P15428 2/20 0.35
ALDH1A1 P00352 1/20 0.35
TP53 P04637 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
HIF1A Q16665 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PTGER4 P35408 1/20 0.35
HDAC4 P56524 1/20 0.34
PDE6D O43924 1/20 0.33
PDE10A Q9Y233 1/20 0.33
PTGES O14684 1/20 0.33
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25972746 0.96 KDM4E (0.41) KDM4EATML3MBTL1HPGDALDH1A1
SCHEMBL25972706 0.96 ALDH1A1 (0.38) KDM4EATML3MBTL1HPGDALDH1A1
SCHEMBL25474001 0.94 KDM4E (0.44) KDM4EATML3MBTL1HPGDPTGER4
SCHEMBL25474003 0.94 KDM4E (0.44) KDM4EATML3MBTL1HPGDPTGER4
SCHEMBL18717897 0.92 KDM4E (0.50) KDM4EATML3MBTL1HPGDALDH1A1
SCHEMBL25972759 0.92 L3MBTL1 (0.50) KDM4EATML3MBTL1HPGDALDH1A1
SCHEMBL25972703 0.92 L3MBTL1 (0.53) KDM4EATML3MBTL1HPGDALDH1A1
SCHEMBL18717907 0.91 KDM4E (0.49) KDM4EATML3MBTL1HPGDALDH1A1
SCHEMBL18717909 0.91 KDM4E (0.49) KDM4EATML3MBTL1HPGDALDH1A1
SCHEMBL18717901 0.91 KDM4E (0.49) KDM4EATML3MBTL1HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250048-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-10 US disclosed
US-20230250048-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250048-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE NOS1, NOM1, NCF1 KDM4E 1616/4885ATM 1439/4885L3MBTL1 687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.