Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20832974 | 1.00 | RAB9A (0.53) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL22260353 | 1.00 | RAB9A (0.53) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL20833288 | 1.00 | RAB9A (0.53) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL22260110 | 0.88 | HPGD (0.54) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL19841237 | 0.86 | CYP2D6 (0.70) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL14227426 | 0.86 | CYP2D6 (0.70) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL3088977 | 0.86 | CYP2D6 (0.70) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL16640675 | 0.86 | CYP2D6 (0.70) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL20833321 | 0.86 | CYP2D6 (0.70) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL16931709 | 0.86 | CYP2D6 (0.70) | RAB9ANPC1CYP1A2HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | ALKBH1, DUT, RNGTT | RAB9A 3746/4885NPC1 3712/4885CYP1A2 4059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.