SCHEMBL25973457

SCHEMBL25973457

CCO[Si](CCCOC(=O)C(C)(C)C)(OCC)OCC

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.35
CYP4A11 Q02928 2/20 0.35
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
PRKCA P17252 1/20 0.33
ALDH1A1 P00352 1/20 0.31
ACHE P22303 6/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1615742 0.89 POLB (0.37) CYP4F2CYP4A11POLBGAANPSR1
SCHEMBL15261081 0.86 CYP4F2 (0.30) CYP4F2CYP4A11POLBGAANPSR1
SCHEMBL4400245 0.86 CYP4F2 (0.37) CYP4F2CYP4A11CYP3A4
SCHEMBL1802610 0.84 CES2 (0.32) ALDH1A1
SCHEMBL15270593 0.84 CYP4F2 (0.34) CYP4F2CYP4A11POLBGAANPSR1
SCHEMBL23312186 0.84 ACHE (0.41) ACHE
SCHEMBL9171371 0.81 ALDH1A1 (0.42) ALDH1A1ACHE
SCHEMBL13058214 0.80 ACHE (0.33) CYP4F2CYP4A11ACHE
SCHEMBL1969735 0.80 ACHE (0.33) CYP4F2CYP4A11ALDH1A1ACHE
SCHEMBL6521209 0.80 ACHE (0.33) CYP4F2CYP4A11ALDH1A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230257553-A1 SYNTHESIS OF SILANE COMPOUNDS MOMENTIVE PERFORMANCE MATERIALS INC. 2023-08-17 US disclosed