SCHEMBL6521209

SCHEMBL6521209

CCO[Si](CCCCCOC(=O)C(C)(C)Br)(OCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ACHE P22303 11/20 0.33
NAAA Q02083 1/20 0.33
CYP4F2 P78329 2/20 0.32
CYP4A11 Q02928 2/20 0.32
FAAH O00519 1/20 0.31
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1969735 1.00 ACHE (0.33) ACHENAAACYP4F2CYP4A11FAAH
SCHEMBL15261081 0.94 CYP4F2 (0.30) CYP4F2CYP4A11
SCHEMBL16426720 0.89 PTGS2 (0.32)
SCHEMBL16426568 0.89 PTGS2 (0.32)
SCHEMBL16426488 0.85
SCHEMBL13058214 0.84 ACHE (0.33) ACHENAAACYP4F2CYP4A11TSHR
SCHEMBL14974356 0.84 HDAC6 (0.32) ACHENAAALMNA
SCHEMBL29912813 0.83 CES2 (0.37) ACHENAAATSHREPHX1
SCHEMBL28902649 0.81 NAAA (0.40) ACHENAAAFAAHTSHRALDH1A1
SCHEMBL651971 0.81 NAAA (0.40) ACHENAAAFAAHTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1597069-A2 NANOMETER-CONTROLLED POLYMERIC THIN FILMS THAT RESIST ADSORPTION OF BIOLOGICAL MOLECULES AND CELLS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-11-23 EP disclosed
US-6946164-B2 Thin nanometer-controlled polymer film gradient E.I. DU PONT NEMOURS AND COMPANY (US) 2005-09-20 US disclosed
WO-2004087872-A2 THIN NANOMETER-CONTROLLED POLYMER FILM GRADIENT E.I. DUPONT DE NEMOURS AND COMPANY (US) 2004-10-14 WO disclosed
US-20040191538-A1 Nanometer-controlled polymeric thin films that resist adsorption of biological molecules and cells E. I. DU PONT DE NEMOURS AND COMPANY 2004-09-30 US disclosed
US-20040191421-A1 Thin nanometer-controlled polymer film grandient E.I. DU PONT DE NEMOURS AND COMPANY 2004-09-30 US disclosed
WO-2004078930-A2 NANOMETER-CONTROLLED POLYMERIC THIN FILMS THAT RESIST ADSORPTION OF BIOLOGICAL MOLECULES AND CELLS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2004-09-16 WO disclosed