SCHEMBL1969735

SCHEMBL1969735

CCO[Si](CCCCCCOC(=O)C(C)(C)Br)(OCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ACHE P22303 11/20 0.33
NAAA Q02083 1/20 0.33
CYP4F2 P78329 2/20 0.32
CYP4A11 Q02928 2/20 0.32
FAAH O00519 1/20 0.31
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6521209 1.00 ACHE (0.33) ACHENAAACYP4F2CYP4A11FAAH
SCHEMBL15261081 0.94 CYP4F2 (0.30) CYP4F2CYP4A11
SCHEMBL16426720 0.89 PTGS2 (0.32)
SCHEMBL16426568 0.89 PTGS2 (0.32)
SCHEMBL16426488 0.85
SCHEMBL13058214 0.84 ACHE (0.33) ACHENAAACYP4F2CYP4A11TSHR
SCHEMBL14974356 0.84 HDAC6 (0.32) ACHENAAALMNA
SCHEMBL29912813 0.83 CES2 (0.37) ACHENAAATSHREPHX1
SCHEMBL28902649 0.81 NAAA (0.40) ACHENAAAFAAHTSHRALDH1A1
SCHEMBL651971 0.81 NAAA (0.40) ACHENAAAFAAHTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552942-B2 Compositions, articles, and methods involving polymer grafted particles MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2026-02-17 US disclosed
US-11739284-B2 Composite material NISSHINBO HOLDINGS INC. (JP) 2023-08-29 US disclosed
EP-3438231-B1 MATERIAL FOR SLIDE MECHANISMS COMPRISING A POLYMER BRUSH UNIV KYOTO (JP) 2023-08-02 EP disclosed
US-20230079151-A1 COMPOSITIONS, ARTICLES, AND METHODS INVOLVING PRESSURE-SENSITIVE ADHESIVES COMPRISING POLYMER-GRAFTED PARTICLES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-03-16 US disclosed
EP-4148097-A2 COMPOSITIONS, ARTICLES, AND METHODS INVOLVING PRESSURE-SENSITIVE ADHESIVES COMPRISING POLYMER-GRAFTED PARTICLES Massachusetts Institute Of Technology (US) 2023-03-15 EP disclosed
US-20230076513-A1 COMPOSITIONS, ARTICLES, AND METHODS INVOLVING POLYMER GRAFTED PARTICLES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-03-09 US disclosed
US-20220389347-A1 COMPOSITE MATERIAL NISSHINBO HOLDINGS INC. (JP) 2022-12-08 US disclosed
EP-4039737-A1 COMPOSITE MATERIAL Nisshinbo Holdings Inc. (JP) 2022-08-10 EP disclosed
EP-3141564-B1 POLYMER BRUSH JAPAN SCIENCE & TECH AGENCY (JP) 2022-07-13 EP disclosed
US-11168170-B2 Clearance narrowing material, clearance narrowing material composite, and article using same KYOTO UNIVERSITY (JP) 2021-11-09 US disclosed
US-20120231346-A1 ELECTROCHEMICAL DEVICE USING SOLID POLYMER ELECTROLYTE USING FINE POLYMER COMPOSITE PARTICLES KYOTO UNIVERSITY (JP) 2012-09-13 US disclosed
EP-2493001-A1 ELECTROCHEMICAL DEVICE USING SOLID POLYMER ELECTROLYTE USING FINE POLYMER COMPOSITE PARTICLES Kyoto University (JP) 2012-08-29 EP disclosed
US-20110223390-A1 POLYMER BRUSH COMPOSITE AND METHOD FOR PRODUCING SAME NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY (JP) 2011-09-15 US disclosed
EP-2335917-A1 POLYMER BRUSH COMPOSITE AND METHOD FOR PRODUCING SAME National University Corporation Tokyo Medical and Dental University (JP) 2011-06-22 EP disclosed
US-20100298499-A1 NOVEL LIVING RADICAL POLYMERIZATION METHOD USING A PHOSPHORUS COMPOUND OR NITROGEN COMPOUND AS A CATALYST KYOTO UNIVERSITY (JP) 2010-11-25 US disclosed
US-20100279118-A1 SURFACE MODIFICATION OF METAL OXIDE NANOPARTICLES SPARKXIS B.V. (NL) 2010-11-04 US disclosed
EP-2242805-A1 SURFACE MODIFICATION OF METAL OXIDE NANOPARTICLES Sparkxis B.V. (NL) 2010-10-27 EP disclosed
WO-2010035799-A1 POLYMER BRUSH COMPOSITE AND METHOD FOR PRODUCING SAME 国立大学法人東京医科歯科大学 (JP) 2010-04-01 WO disclosed
WO-2009087021-A1 SURFACE MODIFICATION OF METAL OXIDE NANOPARTICLES SPARKXIS B.V. (NL) 2009-07-16 WO disclosed
US-20080057310-A1 High-Density Polymer Brush-Coated Hollow Microparticles, Processes For Producing The Same And Applications Of High-Density Polymer Brush-Coated Hollow Microparticles KYOTO UNIVERISTY (JP) 2008-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298499-A1 NOVEL LIVING RADICAL POLYMERIZATION METHOD USING A PHOSPHORUS COMPOUND OR NITROGEN COMPOUND AS A CATALYST PNPO, PPOX, CBR3 ACHE 3066/4885NAAA 849/4885CYP4F2 670/4885
US-12552942-B2 Compositions, articles, and methods involving polymer grafted particles FLNA, MKI67, CD68 ACHE 2219/4885NAAA 3920/4885CYP4F2 3949/4885
US-20100279118-A1 SURFACE MODIFICATION OF METAL OXIDE NANOPARTICLES CD63, SOD1, EPCAM ACHE 485/4885NAAA 736/4885CYP4F2 3496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.