Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HTR1E | P28566 | 1/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4711347 | 0.85 | HDAC4 (0.42) | LMNACYP2C9HSD11B1CYP3A4CYP2D6 | |
| SCHEMBL3553242 | 0.83 | HDAC4 (0.62) | NPSR1LMNAKDM4EHSD11B1HDAC4 | |
| SCHEMBL8572144 | 0.82 | HDAC4 (0.59) | NPSR1LMNAHSD11B1HDAC4OPRL1 | |
| SCHEMBL4711696 | 0.80 | ALDH1A1 (0.59) | MAPTNPSR1LMNAKDM4EHPGD | |
| SCHEMBL19537445 | 0.79 | LMNA (0.50) | NPSR1LMNAHSD11B1HDAC4OPRL1 | |
| SCHEMBL351393 | 0.78 | AKR1C1 (0.55) | LMNACYP2C9HSD11B1CYP3A4CYP2D6 | |
| SCHEMBL5379326 | 0.78 | HSD11B1 (0.45) | MAPTNPSR1HTR1ES1PR3LMNA | |
| SCHEMBL22266637 | 0.78 | LMNA (0.72) | MAPTNPSR1HTR1ES1PR3LMNA | |
| SCHEMBL844453 | 0.77 | OPRM1 (0.53) | MAPTNPSR1HTR1ES1PR3LMNA | |
| SCHEMBL25460818 | 0.77 | HDAC4 (0.73) | MAPTNPSR1LMNAHSD11B1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |