Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | USP1 | O94782 | 11/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25223917 | 0.80 | USP1 (0.45) | DGAT1PTGS2USP1PTGS1 | |
| SCHEMBL18865809 | 0.80 | CYP11B2 (0.47) | SCN9APTGS2USP1PTGS1 | |
| SCHEMBL25223739 | 0.80 | DGAT1 (0.60) | DGAT1PTGS2USP1PTGS1 | |
| SCHEMBL22165900 | 0.79 | MEN1 (0.46) | DGAT1PTGS2USP1PTGS1 | |
| SCHEMBL29429387 | 0.79 | MEN1 (0.46) | DGAT1PTGS2USP1PTGS1 | |
| SCHEMBL31497611 | 0.76 | PTGS2 (0.44) | DGAT1PTGS2USP1PTGS1 | |
| SCHEMBL31661817 | 0.76 | SCN9A (0.46) | SCN9APTGS2USP1PTGS1 | |
| SCHEMBL31661810 | 0.76 | SCN9A (0.46) | SCN9APTGS2USP1PTGS1 | |
| SCHEMBL31497613 | 0.76 | DGAT1 (0.45) | DGAT1PTGS2USP1PTGS1 | |
| SCHEMBL26627860 | 0.76 | USP1 (0.45) | DGAT1PTGS2USP1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023148643-A1 | FUSED BICYCLIC HETEROCYCLYL COMPOUNDS AS USP1 INHIBITORS | AURIGENE ONCOLOGY LIMITED (IN) | 2023-08-10 | — | — | WO | disclosed |