Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 4/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | MAP3K8 | P41279 | 2/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 3/20 | 0.40 |
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2597600 | 0.79 | SYK (0.49) | ABCG2KDRGRM4SYKCDK2 | |
| SCHEMBL4753464 | 0.78 | MAOB (0.74) | MAOBIMPDH2 | |
| SCHEMBL15145210 | 0.77 | KMT2A (0.48) | MAOBSYK | |
| SCHEMBL2597602 | 0.75 | KDR (0.44) | ABCG2KDRGRM4CDK1SYK | |
| SCHEMBL24127052 | 0.72 | ABCG2 (0.56) | ABCG2GRM4AR | |
| SCHEMBL2597608 | 0.71 | CCNT1 (0.47) | CDK1CDK2CDK9 | |
| SCHEMBL3594258 | 0.71 | CTSV (0.56) | MAOBCTSVCTSLSYK | |
| SCHEMBL3589681 | 0.71 | SYK (0.48) | MAOBCTSVCTSLSYKCDK2 | |
| SCHEMBL22273618 | 0.70 | MAP3K8 (0.53) | ABCG2GRM4MAP3K8CDK9 | |
| SCHEMBL427002 | 0.70 | MAOB (0.74) | MAOBIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571856-A1 | COMPOUNDS | BTG International Limited (GB) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011144577-A1 | COMPOUNDS | SENEXIS LIMITED (GB) | 2011-11-24 | — | — | WO | disclosed |
| WO-2011144577-A1 | COMPOUNDS | SENEXIS LIMITED (GB) | 2011-11-24 | — | — | WO | disclosed |