Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | RGS12 | O14924 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11851846 | 0.98 | CA2 (0.62) | CA2CYP3A4HPGDHSD17B10KDM4E | |
| SCHEMBL7055740 | 0.85 | CA2 (0.59) | CA2HPGDHSD17B10KDM4ETSHR | |
| SCHEMBL2396526 | 0.83 | CYP3A4 (0.57) | CA2CYP3A4HPGDHSD17B10KDM4E | |
| SCHEMBL283587 | 0.82 | CA2 (0.71) | CA2HPGDHSD17B10KDM4ETSHR | |
| SCHEMBL1000171 | 0.82 | GAA (0.55) | CA2HPGDHSD17B10KDM4ETSHR | |
| SCHEMBL23665797 | 0.81 | CYP3A4 (0.55) | CA2CYP3A4 | |
| Methane SCHEMBL7951771 | 0.80 | CA2 (0.69) | CA2HPGDHSD17B10KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL2530252 | 0.80 | CA2 (0.69) | CA2HPGDHSD17B10KDM4ETSHR | |
| SCHEMBL19180323 | 0.79 | CYP3A4 (0.52) | CA2CYP3A4 | |
| SCHEMBL2434505 | 0.79 | ALDH1A1 (0.64) | CA2CYP3A4HPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021143923-A1 | BORONIC ACID DERIVATIVES | 首药控股(北京)股份有限公司 | 2021-07-22 | — | — | WO | disclosed |
| US-20130261185-A1 | Benzamide Derivatives As EP4 Receptor Agonists | GLAXO GROUP LIMITED (GB) | 2013-10-03 | — | — | US | disclosed |
| EP-2571860-A1 | 2-PHENYL BENZOYLAMIDES | Pfizer Inc (US) | 2013-03-27 | — | — | EP | disclosed |
| US-20130072519-A1 | 2-PHENYL BENZOYLAMIDES | CONN EDWARD LEE (US) | 2013-03-21 | — | — | US | disclosed |
| US-8314147-B2 | Benzamide derivatives as EP4 receptor agonists | GLAXO GROUP LIMITED (GB) | 2012-11-20 | — | — | US | disclosed |
| EP-1979317-B1 | BENZOISOINDOLE DERIVATIVES FOR THE TREATMENT OF PAIN | GLAXO GROUP LTD (GB) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011145022-A1 | 2-PHENYL BENZOYLAMIDES | PFIZER INC. (US) | 2011-11-24 | — | — | WO | disclosed |
| US-20100273853-A1 | NOVEL ISOINDOL DERIVATIVES AS EP4 RECEPTOR AGONISTS | GLAXO GROUP LIMITED | 2010-10-28 | — | — | US | disclosed |
| EP-2046742-B1 | BENZO [F] ISOINDOLES AS EP4 RECEPTOR AGONISTS | GLAXO GROUP LTD (GB) | 2010-09-22 | — | — | EP | disclosed |
| EP-2081897-B1 | ISOINDOL DERIVATIVES AS EP4 RECEPTOR AGONISTS | GLAXO GROUP LTD (GB) | 2010-09-15 | — | — | EP | disclosed |
| WO-2008012344-A1 | NAPHTHALENE DERIVATIVES USED AS EP4 RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2008-01-31 | — | — | WO | disclosed |
| WO-2008012347-A1 | BENZO [F] ISOINDOLES AS EP4 RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2008-01-31 | — | — | WO | disclosed |
| US-20070269664-A1 | Gas Barrier Laminated Film and Process for Producing the Same | SAI NIPPON PRINTING CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
| US-20070238718-A1 | THIAZOLYL-DIHYDRO-INDAZOLE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-11 | — | — | US | disclosed |
| WO-2007088189-A1 | BENZOISOINDOLE DERIVATIVES FOR THE TREATMENT OF PAIN | GLAXO GROUP LIMITED (GB) | 2007-08-09 | — | — | WO | disclosed |
| WO-2005108374-A1 | INSECTICIDAL DIAZOLE AND TRIAZOLE DERIVATIVES | FMC CORPORATION (US) | 2005-11-17 | — | — | WO | disclosed |
| EP-0757669-B1 | O-ACYL-4-PHENYL-CYCLOHEXANOLS, THEIR SALTS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE, AS WELL AS A METHOD OF PREPARING THEM | BOEHRINGER INGELHEIM PHARMA (DE) | 1998-11-18 | — | — | EP | disclosed |
| EP-0757669-A1 | O-ACYL-4-PHENYL-CYCLOHEXANOLS, THEIR SALTS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE, AS WELL AS A METHOD OF PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029148-A1 | O-ACYL-4-PHENYL-CYCLOHEXANOLS, THEIR SALTS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE, AS WELL AS A METHOD OF PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1995-11-02 | — | — | WO | disclosed |
| US-4239901-A | ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1980-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070269664-A1 | Gas Barrier Laminated Film and Process for Producing the Same | CDH1, VIL1, TET1 | CA2 774/4885CYP3A4 2668/4885HPGD 3570/4885 |
| US-20100273853-A1 | NOVEL ISOINDOL DERIVATIVES AS EP4 RECEPTOR AGONISTS | PTGER4, PTGER1, PTGER3 | CA2 4527/4885CYP3A4 79/4885HPGD 345/4885 |
| US-20130072519-A1 | 2-PHENYL BENZOYLAMIDES | APOB, MTTP, HADHB | CA2 4702/4885CYP3A4 534/4885HPGD 959/4885 |
| US-20130261185-A1 | Benzamide Derivatives As EP4 Receptor Agonists | PTGER4, PTGER1, PTGER3 | CA2 3618/4885CYP3A4 146/4885HPGD 748/4885 |
| US-20070238718-A1 | THIAZOLYL-DIHYDRO-INDAZOLE | CYP3A43, CYP3A5, UGT1A3 | CA2 887/4885CYP3A4 8/4885HPGD 987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.