Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 10/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 10/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 10/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 10/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25969286 | 1.00 | APP (0.38) | APPCTSDBACE1BACE2CHRM2 | |
| SCHEMBL20595799 | 0.72 | SLC6A2 (0.37) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL25970518 | 0.70 | CHRNA7 (0.34) | HSD11B1CYP2C9ALDH1A1 | |
| SCHEMBL25985270 | 0.70 | CHRNA7 (0.34) | HSD11B1CYP2C9ALDH1A1 | |
| SCHEMBL26398488 | 0.69 | SMN1; SMN2 (0.41) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL957217 | 0.63 | HSD11B1 (0.57) | CHRM2CHRM3HSD11B1 | |
| SCHEMBL28154613 | 0.63 | DHODH (0.44) | CTSDBACE1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13986781 | 0.60 | KCNN4 (0.36) | APPBACE1BACE2CHRM2CHRM3 | |
| SCHEMBL13206673 | 0.60 | KCNN4 (0.36) | APPBACE1BACE2CHRM2CHRM3 | |
| SCHEMBL12243272 | 0.60 | TNKS (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | ALKBH1, DUT, RNGTT | APP 3702/4885CTSD 2984/4885BACE1 2690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.