Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25970518 | 1.00 | CHRNA7 (0.34) | CHRNA7TSHRCYP2C9MAPK1ALDH1A1 | |
| SCHEMBL25970342 | 0.71 | CHRNA7 (0.35) | CHRNA7ALDH1A1 | |
| SCHEMBL25980370 | 0.70 | APP (0.38) | CYP2C9ALDH1A1HSD11B1 | |
| SCHEMBL25969286 | 0.70 | APP (0.38) | CYP2C9ALDH1A1HSD11B1 | |
| SCHEMBL25970546 | 0.68 | — | — | |
| SCHEMBL24059773 | 0.61 | ALDH1A1 (0.37) | CHRNA7TSHRCYP2C9MAPK1ALDH1A1 | |
| SCHEMBL6626403 | 0.61 | CNR1 (0.33) | ALDH1A1 | |
| SCHEMBL20794084 | 0.60 | KMT2A (0.31) | — | |
| SCHEMBL15743986 | 0.60 | KMT2A (0.31) | — | |
| SCHEMBL16181383 | 0.58 | ALDH1A1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | ALKBH1, DUT, RNGTT | CHRNA7 2395/4885TSHR 3918/4885CYP2C9 2988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.