SCHEMBL25985295

SCHEMBL25985295

NCCNCCOCCOCc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.45
NAAA Q02083 1/20 0.45
LMNA P02545 1/20 0.45
HTT P42858 1/20 0.44
HTR1A P08908 3/20 0.44
ADRA1D P25100 3/20 0.44
ADRA1A P35348 3/20 0.44
ADRA1B P35368 3/20 0.44
DRD2 P14416 2/20 0.42
DRD4 P21917 2/20 0.42
DRD3 P35462 2/20 0.42
SIGMAR1 Q99720 1/20 0.41
GAA P10253 1/20 0.41
ADRB2 P07550 1/20 0.40
ADRB1 P08588 1/20 0.40
ADRB3 P13945 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21207996 0.97 TSHR (0.44) TSHRSMN1; SMN2NAAALMNAHTT
SCHEMBL6239315 0.96 TSHR (0.50) TSHRSMN1; SMN2LMNAHTTHTR1A
SCHEMBL8760726 0.87 TSHR (0.61) TSHRSMN1; SMN2LMNAHTTHTR1A
SCHEMBL11935005 0.87 SIGMAR1 (0.49) TSHRSIGMAR1
SCHEMBL7134228 0.85 TSHR (0.58) TSHRSMN1; SMN2LMNAHTTHTR1A
SCHEMBL8160604 0.83 TSHR (0.47) TSHRSMN1; SMN2LMNAHTTHTR1A
SCHEMBL1923484 0.83 DRD2 (0.47) TSHRHTR1AADRA1DADRA1AADRA1B
SCHEMBL2592983 0.83 SMN1; SMN2 (0.49) TSHRSMN1; SMN2NAAALMNAHTT
SCHEMBL31474275 0.82 TSHR (0.50) TSHRSMN1; SMN2LMNAHTTHTR1A
SCHEMBL26922382 0.82 TSHR (0.54) TSHRNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067971-A1 Target Ligand NANOPEPTIDE (QINGDAO) BIOTECHNOLOGY LTD. (CN) 2024-02-29 US disclosed
US-20230257750-A1 SIRNA OF ANGPTL3 AND USE THEREOF NANOPEPTIDE (QINGDAO) BIOTECHNOLOGY LTD. (CN) 2023-08-17 US disclosed