Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11935005 | 0.87 | SIGMAR1 (0.49) | TSHRSIGMAR1CHRM2 | |
| SCHEMBL6239315 | 0.86 | TSHR (0.50) | DRD2DRD4DRD3TSHRSIGMAR1 | |
| SCHEMBL16620502 | 0.85 | TSHR (0.54) | DRD2DRD4DRD3TSHRSIGMAR1 | |
| SCHEMBL2782 | 0.85 | TSHR (0.58) | TSHR | |
| SCHEMBL4574564 | 0.83 | TSHR (0.56) | TSHR | |
| SCHEMBL21207996 | 0.83 | TSHR (0.44) | DRD2DRD4DRD3TSHRHTR1A | |
| SCHEMBL1343622 | 0.83 | NPC1 (0.57) | DRD2DRD4DRD3TSHRSIGMAR1 | |
| SCHEMBL12147816 | 0.83 | NPC1 (0.50) | DRD2DRD4DRD3TSHRSIGMAR1 | |
| SCHEMBL25985295 | 0.83 | TSHR (0.47) | DRD2DRD4DRD3TSHRSIGMAR1 | |
| SCHEMBL15341674 | 0.82 | MAOA (0.62) | DRD2DRD4DRD3TSHRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981944-B1 | EPOXY BASED COATINGS | PPG BV (NL) | 2016-01-20 | — | — | EP | disclosed |
| EP-1504051-B1 | ORGANO-FUNCTIONAL POLYSILOXANES | SIGMAKALON SERVICES B V (NL) | 2011-06-08 | — | — | EP | disclosed |
| US-20090068473-A1 | Epoxy Based Coatings | PPG B.V. (NL) | 2009-03-12 | — | — | US | disclosed |
| EP-1981944-A1 | EPOXY BASED COATINGS | PPG B.V. (NL) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007054304-A1 | EPOXY BASED COATINGS | PPG B.V. (NL) | 2007-05-18 | — | — | WO | disclosed |
| US-7118621-B2 | Organo-functional polysiloxanes | SIGMAKALON SERVICES B.V. (NL) | 2006-10-10 | — | — | US | disclosed |
| US-20050202257-A1 | Organo-functional polysiloxanes | SIGMAKALON SERVICES B.V. (NL) | 2005-09-15 | — | — | US | disclosed |
| US-20050148752-A1 | Amino-functional polysiloxanes and their use in coatings | SIGMAKALON SERVICES B.V. (NL) | 2005-07-07 | — | — | US | disclosed |
| EP-1526150-A1 | Anti-skid coating compositions | SigmaKalon Services B.V. (NL) | 2005-04-27 | — | — | EP | disclosed |
| EP-1504051-A1 | ORGANO-FUNCTIONAL POLYSILOXANES | SigmaKalon Services B.V. (NL) | 2005-02-09 | — | — | EP | disclosed |
| EP-1501884-A1 | AMINO-FUNCTIONAL POLYSILOXANES AND THEIR USE IN COATINGS | SigmaKalon Services B.V. (NL) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003093352-A1 | AMINO-FUNCTIONAL POLYSILOXANES AND THEIR USE IN COATINGS | SIGMAKALON SERVICES B.V. (NL) | 2003-11-13 | — | — | WO | disclosed |
| WO-2003093350-A1 | ORGANO-FUNCTIONAL POLYSILOXANES | SIGMAKALON SERVICES B.V. (NL) | 2003-11-13 | — | — | WO | disclosed |
| EP-1361245-A1 | Amino-functional polysiloxanes | SigmaKalon Group B.V. (NL) | 2003-11-12 | — | — | EP | disclosed |
| EP-1359182-A1 | Organo-functional polysiloxanes | SigmaKalon Group B.V. (NL) | 2003-11-05 | — | — | EP | disclosed |
| WO-2003043973-A2 | AMINE PHENOLIC COMPOUNDS AND THEIR USE AS HARDENERS AND/OR ACCELERATORS IN EPOXY COATINGS | SIGMA COATINGS B.V. (NL) | 2003-05-30 | — | — | WO | disclosed |
| EP-1314716-A1 | Amine phenolic compounds and their use as hardener and/or accelerators in epoxy coatings | SIGMA COATINGS B.V. (NL) | 2003-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050202257-A1 | Organo-functional polysiloxanes | H1-3, HAO2, LPO | DRD2 999/4885DRD4 715/4885DRD3 535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.