Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 8/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12185417 | 0.83 | OPRM1 (0.42) | ALDH1A1MDM2CYP2D6MEN1KMT2A | |
| SCHEMBL2598806 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MDM2CYP2D6MEN1KMT2A | |
| SCHEMBL2597754 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MDM2CYP2D6MEN1KMT2A | |
| SCHEMBL2599307 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MDM2CYP2D6MEN1KMT2A | |
| SCHEMBL2599267 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MDM2CYP2D6MEN1KMT2A | |
| SCHEMBL2598812 | 0.73 | ALDH1A1 (0.42) | ALDH1A1MDM2TP53THRBTDP1 | |
| SCHEMBL12185427 | 0.67 | ALDH1A1 (0.40) | ALDH1A1MDM2MEN1KMT2ACYP1A2 | |
| SCHEMBL29602910 | 0.65 | ALDH1A1 (0.46) | ALDH1A1MDM2CYP2D6MEN1KMT2A | |
| SCHEMBL12185862 | 0.62 | CTRB1 (0.42) | ALDH1A1MDM2TP53 | |
| SCHEMBL2597761 | 0.62 | ATM (0.41) | ALDH1A1MDM2MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571860-A1 | 2-PHENYL BENZOYLAMIDES | Pfizer Inc (US) | 2013-03-27 | — | — | EP | disclosed |
| US-20130072519-A1 | 2-PHENYL BENZOYLAMIDES | CONN EDWARD LEE (US) | 2013-03-21 | — | — | US | disclosed |
| WO-2011145022-A1 | 2-PHENYL BENZOYLAMIDES | PFIZER INC. (US) | 2011-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072519-A1 | 2-PHENYL BENZOYLAMIDES | APOB, MTTP, HADHB | ALDH1A1 885/4885MDM2 2967/4885CYP2D6 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.