Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.51 |
| ▸ | LIPE | Q05469 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.44 |
| ▸ | AADAC | P22760 | 1/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25987700 | 1.00 | EPHX2 (0.51) | EPHX2LIPEMAPTTP53SMN1; SMN2 | |
| SCHEMBL10133222 | 0.78 | NPY5R (0.56) | EPHX2LIPEMAPTTP53SMN1; SMN2 | |
| SCHEMBL10114314 | 0.78 | NPY5R (0.56) | EPHX2LIPEMAPTTP53SMN1; SMN2 | |
| SCHEMBL13204285 | 0.77 | EPHX2 (0.55) | EPHX2LIPEMAPTTP53SMN1; SMN2 | |
| SCHEMBL10114677 | 0.77 | EPHX2 (0.55) | EPHX2LIPEMAPTTP53SMN1; SMN2 | |
| SCHEMBL23418851 | 0.76 | EPHX2 (0.63) | EPHX2LIPEEPHX1 | |
| SCHEMBL23419215 | 0.76 | EPHX2 (0.63) | EPHX2LIPEEPHX1 | |
| SCHEMBL23390096 | 0.75 | LIPE (0.66) | EPHX2LIPEMAPTTP53SMN1; SMN2 | |
| SCHEMBL18960368 | 0.74 | EPHX2 (0.64) | EPHX2LIPEMAPTTP53SMN1; SMN2 | |
| SCHEMBL23389188 | 0.74 | KMT2A (0.52) | EPHX2EPHX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230202974-A1 | CASPASE 6 INHIBITORS AND USES THEREOF | UNIV CALIFORNIA (US) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202974-A1 | CASPASE 6 INHIBITORS AND USES THEREOF | CASP6, CASP1, CASP10 | EPHX2 3551/4885LIPE 898/4885MAPT 1209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.