Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 4/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.52 |
| ▸ | DAO | P14920 | 3/20 | 0.46 |
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | KDM5A | P29375 | 3/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31625660 | 1.00 | PDE3B (0.52) | PDE3BPDE3ADAOPARP1KDM5A | |
| SCHEMBL2300648 | 0.86 | PARP1 (0.55) | PDE3BPDE3ADAOPARP1KDM5A | |
| SCHEMBL4769832 | 0.79 | PARP1 (0.62) | DAOPARP1KDM5AKDM4EGABRP | |
| SCHEMBL9533317 | 0.79 | PARP1 (0.62) | PDE3BPDE3ADAOPARP1FEN1 | |
| SCHEMBL5381840 | 0.76 | ALDH1A1 (0.50) | PDE3BPDE3ADAOPARP1ACHE | |
| SCHEMBL22766047 | 0.74 | HASPIN (0.57) | PDE3BPDE3ADAOPIM1GRIA1 | |
| SCHEMBL16083577 | 0.71 | CHUK (0.38) | PDE3BPDE3ADAOPARP1KDM5A | |
| SCHEMBL12396546 | 0.70 | ACHE (0.61) | PDE3BPDE3ADAOPARP1FEN1 | |
| SCHEMBL17425916 | 0.69 | — | — | |
| SCHEMBL31192609 | 0.69 | PDE3B (1.00) | PDE3BPDE3AGRIA1CACNG8CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 316 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024174953-A1 | BENZIMIDAZOLE DERIVATIVE AND MEDICAL USE THEREOF | 苏州隆博泰药业有限公司 | 2024-08-29 | — | — | WO | claimed |
| WO-2023220370-A1 | BRUTON TYROSINE KINASE INHIBITORS FOR USE IN THE TREATMENT OF MYELIN OLIGODENDROCYTE GLYCOPROTEIN ANTIBODY DISEASE (MOGAD) | GENZYME CORPORATION (US) | 2023-11-16 | — | — | WO | claimed |
| EP-4139306-A1 | KV3 ENHANCERS FOR THE TREATMENT OF COGNITIVE DISORDERS | F. Hoffmann-La Roche AG (CH) | 2023-03-01 | — | — | EP | claimed |
| CN-115557929-A | Somatostatin modulators and uses thereof | 克林提克斯医药股份有限公司 | 2023-01-03 | — | — | CN | claimed |
| EP-3414234-A1 | BRUTON'S TYROSINE KINASE INHIBITORS | Zibo Biopolar Changsheng Pharmaceutical Co. Ltd. (CN) | 2018-12-19 | — | — | EP | claimed |
| WO-2018038667-A1 | RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2018-03-01 | — | — | WO | claimed |
| WO-2017066014-A1 | BRUTON'S TYROSINE KINASE INHIBITORS | SUNNYLIFE PHARMA INC. (US) | 2017-04-20 | — | — | WO | claimed |
| US-20090023724-A1 | Heteroaryl compounds, compositions thereof, and methods of treatment therewith | SIGNAL PHARMACEUTICALS, LLC | 2009-01-22 | — | — | US | claimed |
| EP-4637726-A1 | DRUG FORMULATIONS OF (R)-1-(1-ACRYLOYLPIPERIDIN-3-YL)-4-AMINO-3-(4- PHENOXYPHENYL)-1H-IMIDAZO[4,5-C]PYRIDIN-2(3H)-ONE | Principia Biopharma Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| EP-4637726-A1 | DRUG FORMULATIONS OF (R)-1-(1-ACRYLOYLPIPERIDIN-3-YL)-4-AMINO-3-(4- PHENOXYPHENYL)-1H-IMIDAZO[4,5-C]PYRIDIN-2(3H)-ONE | Principia Biopharma Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| US-20250326725-A1 | PI4-Kinase Inhibitors and Methods of Using the Same | UNIV LELAND STANFORD JUNIOR (US) | 2025-10-23 | — | — | US | disclosed |
| US-12415788-B2 | PI4-kinase inhibitors and methods of using the same | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2025-09-16 | — | — | US | disclosed |
| US-20250197402-A1 | Tyrosine Kinase Inhibitors | PRINCIPIA BIOPHARMA INC. (US) | 2025-06-19 | — | — | US | disclosed |
| WO-2024137604-A8 | DRUG FORMULATIONS OF (R)-1-(1-ACRYLOYLPIPERIDIN-3-YL)-4-AMINO-3-(4- PHENOXYPHENYL)-1H-IMIDAZO[4,5-C]PYRIDIN-2(3H)-ONE | PRINCIPIA BIOPHARMA INC. (US) | 2025-06-12 | — | — | WO | disclosed |
| WO-2002030886-A2 | HETEROCYCLIC ANGIOGENESIS INHIBITORS | MATTHEWS BARRY R (AU) | 2002-04-18 | — | — | WO | disclosed |
| US-5389627-A | Cephalosporins effective against gramnegative bacteria | CHEIL FOODS & CHEMICALS (KR) | 1995-02-14 | — | — | US | disclosed |
| WO-1994029321-A1 | NOVEL CEPHEM COMPOUNDS | CHEIL FOODS & CHEMICALS INC. (KR) | 1994-12-22 | — | — | WO | disclosed |
| EP-0589914-A1 | NOVEL 3-FUSED PYRIDINIUMMETHYL CEPHALOSPORINS | CHEIL FOODS & CHEMICALS, INC. (KR) | 1994-04-06 | — | — | EP | disclosed |
| US-5281589-A | Pharmaceuticals | CHEIL FOODS & CHEMICALS, INC. (KR) | 1994-01-25 | — | — | US | disclosed |
| WO-1992022556-A1 | NOVEL 3-FUSED PYRIDINIUMMETHYL CEPHALOSPORINS | CHEIL FOODS & CHEMICALS, INC. (KR) | 1992-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250326725-A1 | PI4-Kinase Inhibitors and Methods of Using the Same | PI4KB, PI4KA, PI4K2A | PDE3B 3459/4885PDE3A 3290/4885DAO 2142/4885 |
| US-12415788-B2 | PI4-kinase inhibitors and methods of using the same | PI4KB, PI4KA, PI4K2A | PDE3B 3459/4885PDE3A 3290/4885DAO 2142/4885 |
| US-20090023724-A1 | Heteroaryl compounds, compositions thereof, and methods of treatment therewith | JAK2, PHKG1, PHKG2 | PDE3B 3380/4885PDE3A 3883/4885DAO 2841/4885 |
| US-20250197402-A1 | Tyrosine Kinase Inhibitors | BTK, LYN, SYK | PDE3B 1340/4885PDE3A 1799/4885DAO 1972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.