SCHEMBL25993465

SCHEMBL25993465

Cn1c2ccc(C(C)(C)C)cc2c2c3c(ccc21)oc1ccccc13

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.40
RORA P35398 1/20 0.40
RORC P51449 1/20 0.40
RORB Q92753 1/20 0.40
KIF11 P52732 3/20 0.38
NR1H3 Q13133 1/20 0.38
PON1 P27169 1/20 0.37
MAPT P10636 5/20 0.36
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 3/20 0.36
MEN1 O00255 2/20 0.36
HPGD P15428 2/20 0.36
KMT2A Q03164 2/20 0.36
HTT P42858 1/20 0.36
HSD17B10 Q99714 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
GPR3 P46089 1/20 0.36
NPY5R Q15761 1/20 0.35
HTR1D P28221 1/20 0.35
PIK3CD O00329 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25993476 0.92 KIF11 (0.41) PGRRORARORCRORBKIF11
SCHEMBL25682359 0.91 KIF11 (0.43) PGRRORARORCRORBKIF11
SCHEMBL25682399 0.88 KIF11 (0.43) PGRRORARORCRORBKIF11
SCHEMBL25993436 0.85 PGR (0.39) PGRRORARORCRORBKIF11
SCHEMBL25682005 0.84 KIF11 (0.40) PGRRORARORCRORBKIF11
SCHEMBL18745236 0.83 KDM4E (0.38) PGRRORARORCRORBKIF11
SCHEMBL13183682 0.82 GPR3 (0.50) KIF11MAPTKDM4EALDH1A1MEN1
SCHEMBL25682065 0.82 KIF11 (0.42) PGRRORARORCRORBKIF11
SCHEMBL25993457 0.82 KIF11 (0.42) PGRRORARORCRORBKIF11
SCHEMBL23628219 0.82 BCHE (0.45) PGRRORARORCRORBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265106-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-08-24 US disclosed
US-20230265106-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265106-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING ELEMENT CRY1, CCNE2, CRY2 PGR 3110/4885RORA 630/4885RORC 1177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.