Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19632887 | 0.80 | SMN1; SMN2 (0.62) | POLBSMN1; SMN2GAATERTHPGD | |
| SCHEMBL5757616 | 0.72 | HRH3 (0.56) | ALDH1A1KDM4ECYP3A4CYP2C19HRH3 | |
| SCHEMBL17277592 | 0.67 | CARM1 (0.60) | SMN1; SMN2GAAHPGDALDH1A1KDM4E | |
| SCHEMBL17888266 | 0.67 | CARM1 (0.60) | SMN1; SMN2GAAHPGDALDH1A1KDM4E | |
| SCHEMBL17888267 | 0.67 | CARM1 (0.60) | SMN1; SMN2GAAHPGDALDH1A1KDM4E | |
| SCHEMBL24460681 | 0.66 | KDM4E (0.62) | POLBALDH1A1KDM4EMAPTHRH3 | |
| SCHEMBL17886536 | 0.66 | HRH3 (0.42) | SMN1; SMN2GAAHPGDALDH1A1KDM4E | |
| SCHEMBL17886535 | 0.66 | HRH3 (0.42) | SMN1; SMN2GAAHPGDALDH1A1KDM4E | |
| SCHEMBL17886875 | 0.66 | HRH3 (0.42) | SMN1; SMN2GAAHPGDALDH1A1KDM4E | |
| SCHEMBL21078331 | 0.65 | KDM4E (0.47) | POLBSMN1; SMN2GAAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230202974-A1 | CASPASE 6 INHIBITORS AND USES THEREOF | UNIV CALIFORNIA (US) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202974-A1 | CASPASE 6 INHIBITORS AND USES THEREOF | CASP6, CASP1, CASP10 | POLB 4066/4885SMN1; SMN2 1519/4885GAA 303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.