Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | IGF1R | P08069 | 1/20 | 0.52 |
| ▸ | FLT4 | P35916 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | CD38 | P28907 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30307406 | 0.75 | HTR1A (0.61) | KMT2ALMNAKDM4EALDH1A1POLB | |
| SCHEMBL12670825 | 0.74 | CA12 (0.56) | MEN1KMT2AEGFRIGF1RFLT4 | |
| SCHEMBL8908886 | 0.73 | HTR1A (0.71) | HTR1AADRA1DADRA1AADRA1BKCNH2 | |
| SCHEMBL19664004 | 0.71 | ALDH1A1 (0.53) | MEN1KMT2ACD38MAPTKDM4E | |
| SCHEMBL22191089 | 0.71 | MEN1 (0.57) | MEN1KMT2AEGFRIGF1RFLT4 | |
| SCHEMBL26002036 | 0.71 | FYN (0.45) | MEN1KMT2ACD38LMNAMAPT | |
| SCHEMBL3596432 | 0.70 | MAPT (0.59) | MEN1KMT2AEGFRIGF1RFLT4 | |
| SCHEMBL7508087 | 0.70 | HTR1A (0.67) | MEN1KMT2ALMNAMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL7836977 | 0.70 | PKM (0.52) | LMNAKDM4EHTTCYP2C9KCNH2 | |
| SCHEMBL28187442 | 0.69 | HTR1A (0.56) | EGFRIGF1RFLT4KDRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023153748-A1 | SOS1 INHIBITOR AND DERIVATIVE THEREOF | (주)파로스아이바이오 | 2023-08-17 | — | — | WO | disclosed |