Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15623966 | 0.88 | TSHR (0.50) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL129437 | 0.86 | TSHR (0.62) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL28996621 | 0.85 | TSHR (0.61) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL1398208 | 0.82 | TSHR (0.57) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL15713250 | 0.82 | TSHR (0.53) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| Methacrylic Acid SCHEMBL28781342 | 0.82 | TSHR (0.57) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL10716983 | 0.81 | ALDH1A1 (0.62) | TSHRALDH1A1TDP1THRBLMNA | |
| SCHEMBL38662514 | 0.81 | ALDH1A1 (0.62) | TSHRALDH1A1TDP1THRBLMNA | |
| SCHEMBL4783599 | 0.81 | TSHR (0.56) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL3787597 | 0.81 | ALDH1A1 (0.72) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120276503-A1 | CURABLE DENTAL COMPOSITIONS AND ARTICLES COMPRISING POLYMERIZABLE IONIC LIQUIDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-11-01 | — | — | US | disclosed |
| US-20120101184-A1 | COMPOSITIONS AND ARTICLES COMPRISING POLYMERIZABLE IONIC LIQUID MIXTURE, AND METHODS OF CURING | 3M INNOVATIVE PROPERTIES COMPANY | 2012-04-26 | — | — | US | disclosed |
| US-7495038-B2 | Materials leading to improved dental composites and dental composites made therefrom | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101184-A1 | COMPOSITIONS AND ARTICLES COMPRISING POLYMERIZABLE IONIC LIQUID MIXTURE, AND METHODS OF CURING | ELOVL3, ELOVL6, ELOVL1 | TSHR 4730/4885ALDH1A1 3927/4885TDP1 1366/4885 |
| US-20120276503-A1 | CURABLE DENTAL COMPOSITIONS AND ARTICLES COMPRISING POLYMERIZABLE IONIC LIQUIDS | POLL, ELL, ESD | TSHR 4806/4885ALDH1A1 416/4885TDP1 826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.