Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | HTR2B | P41595 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | MLNR | O43193 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2327539 | 0.94 | ALDH1A1 (0.64) | ALDH1A1ALOX15MEN1KMT2ALMNA | |
| SCHEMBL6261397 | 0.88 | ALOX15 (0.74) | ALDH1A1ALOX15MEN1KMT2ALMNA | |
| SCHEMBL8556384 | 0.88 | MEN1 (0.60) | ALDH1A1ALOX15MEN1KMT2ALMNA | |
| Pyrrocaine SCHEMBL25718 | 0.88 | MEN1 (0.70) | ALDH1A1ALOX15MEN1KMT2ALMNA | |
| Pincainide SCHEMBL2110148 | 0.86 | MEN1 (0.73) | ALDH1A1MEN1KMT2ALMNAADRB1 | |
| SCHEMBL22407740 | 0.86 | MEN1 (0.73) | ALDH1A1MEN1KMT2ALMNAADRB1 | |
| Pyrrocaine SCHEMBL10757216 | 0.86 | MEN1 (0.68) | ALDH1A1ALOX15MEN1KMT2ALMNA | |
| SCHEMBL2096761 | 0.86 | MEN1 (0.73) | ALDH1A1MEN1KMT2ALMNAADRB1 | |
| Pyrrocaine SCHEMBL1651381 | 0.85 | MEN1 (0.67) | ALDH1A1ALOX15MEN1KMT2ALMNA | |
| SCHEMBL12598795 | 0.84 | CYP3A4 (0.70) | ALDH1A1ALOX15MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230255958-A1 | METHODS OF TREATMENT FOR GASTROINTESTINAL MOTILITY DISORDERS | VANDERBILT UNIVERSITY | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230255958-A1 | METHODS OF TREATMENT FOR GASTROINTESTINAL MOTILITY DISORDERS | SLC10A2, KCNN3, FABP6 | ALDH1A1 2084/4885ALOX15 1278/4885MEN1 1865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.